Table 2 Univariate and multivariate logistic regression analysis for patients with malignant primary osseous neoplasms by lung metastasis
Characteristic | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | |
Age | ||||
< 30 | Reference | Reference | ||
> 30 | 0.472 (0.391–0.569) | < 0.001 | 0.902 (0.713–1.141) | 0.391 |
Race | ||||
White | Reference | NI | ||
Black | 1.305 (0.971–1.755) | 0.078 | ||
Other1 | 0.919 (0.641–1.317) | 0.646 | ||
Unknown | 1.138 (0.397–3.261) | 0.810 | ||
Gender | ||||
Male | Reference | Reference | ||
Female | 1.311 (1.084–1.586) | 0.005 | 1.243 (1.020–1.516) | 0.031 |
Primary site | ||||
Extremity | Reference | Reference | ||
Axial | 0.688 (0.570–0.830) | < 0.001 | 1.065 (0.860–1.319) | 0.563 |
Grade | ||||
Low grade | Reference | Reference | ||
High grade | 5.346 (3.636–7.862) | < 0.001 | 5.197 (3.328–8.117) | < 0.001 |
Unknown | 6.435 (4.239–9.770) | < 0.001 | 5.106 (3.223–8.088) | < 0.001 |
Tumor size | ||||
< 5 | Reference | Reference | ||
> 5 | 8.102 (5.409–12.134) | < 0.001 | 3.528 (2.370–5.251) | < 0.001 |
Unknown | 6.017 (4.003–9.043) | < 0.001 | 4.346 (2.831–6.673) | < 0.001 |
Histology type | ||||
Osteosarcoma | Reference | 1.432 (1.020–2.009) | 0.038 | |
Ewing sarcoma | 1.219 (0.949–1.564) | 0.121 | 1.597 (1.073–2.377) | 0.021 |
Chondrosarcoma | 0.298 (0.225–0.394) | < 0.001 | Reference | |
Squamous cell carcinoma | 0.311 (0.112–0.860) | 0.024 | 1.233 (0.420–3.620) | 0.704 |
Spindle cell sarcoma | 1.054 (0.509–2.190) | 0.884 | 1.749 (0.797–3.841) | 0.163 |
Chordoma | 0.058 (0.024–0.141) | < 0.001 | 0.102 (0.04–0.261) | < 0.001 |
Giant cell sarcoma | 0.754 (0.423–1.344) | 0.338 | 1.027 (0.545–1.934) | 0.934 |
Small cell sarcoma | 3.520 (0.585–21.183) | 0.169 | 4.677 (0.700–31.234) | 0.111 |
Epithelioid sarcoma | 1.112 (0.375–3.297) | 0.849 | 1.807 (0.576–5.668) | 0.310 |
Small round cell tumor | 3.520 (0.585–21.183) | 0.169 | 5.216 (0.761–35.758) | 0.093 |
Fibrosarcoma | 0.782 (0.367–1.665) | 0.524 | 1.505 (0.672–3.309) | 0.321 |
Adamantinoma | NA | 0.998 | NA | 0.998 |
Hemangiosarcoma | 0.459 (0.164–1.288) | 0.139 | 0.775 (0.263–2.287) | 0.645 |
Synovial sarcoma | 1.760 (0.563–5.505) | 0.331 | 2.858 (0.852–9.591) | 0.089 |
Leiomyosarcoma | 0.220 (0.030–1.634) | 0.139 | 0.386 (0.05–2.946) | 0.358 |
Other | 1.127 (0.773–1.644) | 0.534 | 1.572 (0.992–2.493) | 0.054 |