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Table 2 Univariate and multivariate logistic regression analysis for patients with malignant primary osseous neoplasms by lung metastasis

From: Risk factors for lung metastasis at presentation with malignant primary osseous neoplasms: a population-based study

CharacteristicUnivariate analysisMultivariate analysis
OR (95% CI)POR (95% CI)P
Age
 < 30Reference Reference 
> 300.472 (0.391–0.569)< 0.0010.902 (0.713–1.141)0.391
Race
 WhiteReference NI 
 Black1.305 (0.971–1.755)0.078  
 Other10.919 (0.641–1.317)0.646  
 Unknown1.138 (0.397–3.261)0.810  
Gender
 MaleReference Reference 
 Female1.311 (1.084–1.586)0.0051.243 (1.020–1.516)0.031
Primary site
 ExtremityReference Reference 
 Axial0.688 (0.570–0.830)< 0.0011.065 (0.860–1.319)0.563
Grade
 Low gradeReference Reference 
 High grade5.346 (3.636–7.862)< 0.0015.197 (3.328–8.117)< 0.001
 Unknown6.435 (4.239–9.770)< 0.0015.106 (3.223–8.088)< 0.001
Tumor size
 < 5Reference Reference 
> 58.102 (5.409–12.134)< 0.0013.528 (2.370–5.251)< 0.001
 Unknown6.017 (4.003–9.043)< 0.0014.346 (2.831–6.673)< 0.001
Histology type
 OsteosarcomaReference 1.432 (1.020–2.009)0.038
 Ewing sarcoma1.219 (0.949–1.564)0.1211.597 (1.073–2.377)0.021
 Chondrosarcoma0.298 (0.225–0.394)< 0.001Reference 
 Squamous cell carcinoma0.311 (0.112–0.860)0.0241.233 (0.420–3.620)0.704
 Spindle cell sarcoma1.054 (0.509–2.190)0.8841.749 (0.797–3.841)0.163
 Chordoma0.058 (0.024–0.141)< 0.0010.102 (0.04–0.261)< 0.001
 Giant cell sarcoma0.754 (0.423–1.344)0.3381.027 (0.545–1.934)0.934
 Small cell sarcoma3.520 (0.585–21.183)0.1694.677 (0.700–31.234)0.111
 Epithelioid sarcoma1.112 (0.375–3.297)0.8491.807 (0.576–5.668)0.310
 Small round cell tumor3.520 (0.585–21.183)0.1695.216 (0.761–35.758)0.093
 Fibrosarcoma0.782 (0.367–1.665)0.5241.505 (0.672–3.309)0.321
 AdamantinomaNA0.998NA0.998
 Hemangiosarcoma0.459 (0.164–1.288)0.1390.775 (0.263–2.287)0.645
 Synovial sarcoma1.760 (0.563–5.505)0.3312.858 (0.852–9.591)0.089
 Leiomyosarcoma0.220 (0.030–1.634)0.1390.386 (0.05–2.946)0.358
 Other1.127 (0.773–1.644)0.5341.572 (0.992–2.493)0.054
  1. OR odds ratio, CI confidence interval, NI not included. n = 4459
  2. 1Including American Indian/Alaska Native, Asian/Pacific Islander