Table 1 Characteristics of patients with malignant primary osseous neoplasms by lung metastasis

Age

< 0.001

 < 30

1810 (40.6)

1521 (38.5)

289 (57.0)

 > 30

2649 (59.4)

2431 (61.5)

218 (43.0)

Race

0.312

 White

3667 (82.2)

3258 (82.4)

409 (80.7)

 Black

412 (9.2)

354 (9.0)

58 (11.4)

 Other¹

348 (7.8)

312 (7.9)

36 (7.1)

 Unknown

32 (0.7)

28 (0.7)

4 (0.8)

Gender

0.005

 Male

2530 (56.7)

2213 (56.0)

317 (62.5)

 Female

1929 (43.3)

1739 (44.0)

190 (37.5)

Primary site

< 0.001

 Extremity

2273 (51.0)

1973 (49.9)

300 (59.2)

 Axial

2186 (49.0)

1979 (50.1)

207 (40.8)

Grade

< 0.001

 Low grade

1144 (25.7)

1117 (28.3)

27 (5.3)

 High grade

1606 (36.0)

1343 (34.0)

263 (51.9)

 Unknown

1709 (38.3)

1492 (37.8)

217 (42.8)

Tumor size

< 0.001

 < 5

1029 (23.1)

1000 (25.3)

29 (5.7)

 > 5

2667 (59.8)

2309 (58.4)

358 (70.6)

 Unknown

763 (17.1)

643 (16.3)

120 (23.7)

Histology type

< 0.001

 Osteosarcoma

1457 (32.7)

1225 (31.0)

232 (45.8)

 Ewing sarcoma

592 (13.3)

481 (12.2)

111 (21.9)

 Chondrosarcoma

1292 (29.0)

1223 (30.9)

69 (13.6)

 Squamous cell carcinoma

72 (1.6)

68 (1.7)

4 (0.8)

 Spindle cell sarcoma

54 (1.2)

45 (1.1)

9 (1.8)

 Chordoma

461 (10.3)

456 (11.5)

5 (1.0)

 Giant cell sarcoma

112 (2.5)

98 (2.5)

14 (2.8)

 Small cell sarcoma

5 (0.1)

3 (0.1)

2 (0.4)

 Epithelioid sarcoma

23 (0.5)

19 (0.4)

4 (0.8)

 Small round cell tumor

5 (0.1)

3 (0.1)

2 (0.4)

 Fibrosarcoma

62 (1.4)

54 (1.4)

8 (1.6)

 Adamantinoma

17 (0.4)

17 (0.4)

0 (0)

 Hemangiosarcoma

50 (1.1)

46 (1.2)

4 (0.8)

 Synovial sarcoma

16 (0.4)

12 (0.3)

4 (0.8)

 Leiomyosarcoma

25 (5.6)

24 (0.9)

1 (0.2)

 Other

216 (4.8)

178 (4.5)

38 (7.5)