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Table 5 The association of genotypes in RETN genes with the clinical phenotypes

From: Variants in RETN gene are associated with steroid-induced osteonecrosis of the femoral head risk among Han Chinese people

SNP

Genotype

TC (mmol/L)

TG (mmol/L)

HDL-C (mmol/L)

LDL-C (mmol/L)

TC/HDL-C

TG/HDL-C

LDL-C/HDL-C

rs34861192

AA(n = 1)

4.84

2.91

1.08

2.61

4.48

2.69

2.42

AG(n = 52)

4.71 ± 0.93

1.97 ± 1.32

1.05 ± 0.27

2.75 ± 0.77

4.72 ± 2.48

2.13 ± 1.79

2.75 ± 0.86

GG(n = 146)

4.43 ± 0.91

1.78 ± 1.50

1.07 ± 0.27

2.60 ± 0.76

4.30 ± 1.15

1.87 ± 1.98

2.52 ± 0.81

p

0.156

0.551

0.073

0.587

0.090

0.653

0.670

rs3219175

AA (n = 1)

4.84

2.91

1.08

2.61

4.48

2.69

2.42

AG (n = 50)

4.75 ± 0.93

2.01 ± 1.33

1.05 ± 0.28

2.77 ± 0.78

4.76 ± 1.23

2.17 ± 1.82

2.77 ± 0.87

GG (n = 146)

4.42 ± 0.91

1.78 ± 1.50

1.07 ± 0.27

2.59 ± 0.76

4.29 ± 1.15

1.87 ± 1.98

2.51 ± 0.80

p

0.097

0.492

0.835

0.356

0.058

0.587

0.152

rs3745368

AA (n = 2)

4.11 ± 0.64

1.13 ± 0.01

1.14 ± 0.23

2.20 ± 0.80

4.38 ± 1.67

1.18 ± 0.26

2.40 ± 1.37

AG (n = 41)

4.37 ± 0.95

1.76 ± 1.61

1.04 ± 0.22

2.56 ± 0.81

4.35 ± 1.23

1.92 ± 2.24

2.55 ± 0.88

GG (n = 156)

4.54 ± 0.91

1.87 ± 1.42

1.07 ± 0.28

2.66 ± 0.76

4.43 ± 1.17

1.96 ± 1.86

2.59 ± 0.80

p

0.453

0.722

0.718

0.531

0.927

0.853

0.912

rs1477341

AA(n = 32)

2.00 ± 1.40

4.41 ± 0.82

1.01 ± 0.22

2.50 ± 0.71

4.52 ± 1.15

2.17 ± 1.69

2.56 ± 0.84

AT(n = 90)

1.96 ± 1.47

4.57 ± 0.94

1.04 ± 0.25

2.71 ± 0.78

4.58 ± 1.16

2.10 ± 1.98

2.70 ± 0.79

TT(n = 68)

1.62 ± 1.53

4.45 ± 0.97

1.13 ± 0.30

2.58 ± 0.78

4.12 ± 1.19

1.65 ± 2.06

2.39 ± 0.84

p

0.302

0.588

0.049*

0.315

0.049*

0.292

0.066

  1. p values were calculated by logistic regression
  2. Italicized values are statistically significant
  3. *p < 0.05 indicates statistical significance