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Table 4 The association of genotypes in RETN genes with the clinical phenotypes

From: Variants in RETN gene are associated with steroid-induced osteonecrosis of the femoral head risk among Han Chinese people

SNP

Genotype

Gender

p

Hip lesions

p

Clinical stages

p

Male

Female

Unilateral

Bilateral

Stage II

Stage III

Stage IV

rs7408174

CC

8

6

0.775

5

9

0.285

3

5

6

0.694

CT

42

35

18

59

19

39

19

TT

64

43

36

71

24

50

33

rs34861192

AA

0

1

0.465

0

1

0.547

0

1

0

0.193

AG

29

23

18

34

15

28

9

GG

86

60

41

105

32

65

49

rs34124816

AA

94

77

0.105

51

120

0.650

41

78

52

0.557

CA

20

6

8

18

6

14

6

CC

1

1

0

2

0

2

0

rs3219175

AA

0

1

0.470

0

1

0.592

0

1

0

0.216

AG

28

22

17

33

15

26

9

GG

86

60

41

105

31

66

49

rs3745367

AA

12

9

0.775

3

18

0.263

3

14

4

0.049*

AG

48

39

27

60

24

44

19

GG

55

36

29

62

20

36

35

rs3745368

AA

1

1

0.308

0

2

0.650

0

2

0

0.613

AG

28

13

12

29

9

21

11

GG

86

70

47

109

38

71

47

rs3745369

CC

8

6

0.876

4

10

0.059

2

11

1

0.161

CG

50

40

20

70

20

41

29

GG

54

37

35

56

24

41

26

rs1477341

AA

24

8

0.063

9

23

0.809

6

21

5

0.090

AT

48

42

25

65

21

43

26

TT

35

33

22

46

17

25

26

  1. p values were calculated by logistic regression
  2. Italicized value is statistically significant
  3. *p < 0.05 indicates statistical significance