Variants in RETN gene are associated with steroid-induced osteonecrosis of the femoral head risk among Han Chinese people

Table 2 Basic information of candidate SNPs of RETN gene in this study

SNP ID	Gene	Band	Alleles A/B	MAF		HWE-p^a	OR (95% CI)	p^b value
SNP ID	Gene	Band	Alleles A/B	Case	Control	HWE-p^a	OR (95% CI)	p^b value
rs7408174	RETN	19	C/T	0.265	0.233	0.556	1.19(0.86–1.64)	0.287
rs34861192	RETN	19	A/G	0.136	0.198	0.654	0.64(0.44–0.93)	0.019*
rs34124816	RETN	19	A/C	0.075	0.100	1.000	0.73(0.45–1.20)	0.219
rs3219175	RETN	19	A/G	0.132	0.200	0.⁶⁵⁹	0.61(0.42–0.89)	0.010*
rs3745367	RETN	19	A/G	0.324	0.390	0.882	0.75(0.56–1.00)	0.052
rs3745368	RETN	19	A/G	0.113	0.171	1.000	0.62(0.41–0.93)	0.020*
rs3745369	RETN	19	C/G	0.303	0.337	0.636	0.85(0.63–1.15)	0.305
rs1477341	RETN	19	A/T	0.405	0.480	0.479	0.74(0.56–0.98)	0.036*

SNP single-nucleotide polymorphism, HWE Hardy–Weinberg equilibrium, OR odds ratio, 95% CI 95% confidence interval, MAF minor allele frequency
p^a and p^b were calculated by chi-squared test
Italicized values are statistically significant
*p < 0.05 indicates statistical significance

ISSN: 1749-799X