From: Establishment of an in vivo rat model for chronic musculoskeletal implant infection
Inoculum (CFU) | 0.7 (0.7–0.8) 104 | 1.1 (1.1–1.1) 104 | 0.9 (0.7–1.1) 103 | 1.4 (1.3–1.4) 102 |
---|---|---|---|---|
Time period (days) | 20 | 42 | 42 | 42 |
Rats (n) | 4 | 2a | 3 | 2a |
Bone grafts (n) | 8 | 4 | 6 | 4 |
Steel plates (n)b | 12 | 6 | 9 | 6 |
Bacterial growth in bone grafts (total CFU) | 110 (± 50)·105 | 69 (± 41)·105 | 96 (± 65)·105 | 170 (± 36)·105 |
Bacterial growth in sonicate fluid (CFU/ml) | 217 (± 122)·102 | 31 (± 22)·102 | 68 (± 112) 102 | 32 (± 21) 102 |