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Table 1 Steel implants infected with S. epidermidis ATCC 35984 in an in vivo rat model

From: Establishment of an in vivo rat model for chronic musculoskeletal implant infection

Inoculum (CFU)0.7 (0.7–0.8) 1041.1 (1.1–1.1) 1040.9 (0.7–1.1) 1031.4 (1.3–1.4) 102
Time period (days)20424242
Rats (n)42a32a
Bone grafts (n)8464
Steel plates (n)b12696
Bacterial growth in bone grafts (total CFU)110 (± 50)·10569 (± 41)·10596 (± 65)·105170 (± 36)·105
Bacterial growth in sonicate fluid (CFU/ml)217 (± 122)·10231 (± 22)·10268 (± 112) 10232 (± 21) 102
  1. The total number of CFU of S. epidermidis ATCC 35984 are listed as a result of different time periods for infection and different inoculum size (experiments I and II). The number of CFU recovered from bone grafts and sonicate fluid are presented as mean (± 1 SD).
  2. aOne rat died postoperatively. In one rat, the bone grafts were contaminated
  3. bFrom each animal, one steel plate was processed for SEM and three steel plates were sonicated