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Fig. 8 | Journal of Orthopaedic Surgery and Research

Fig. 8

From: Mesenchymal stem cells genetically engineered to express platelet-derived growth factor and heme oxygenase-1 ameliorate osteoarthritis in a canine model

Fig. 8

Assessment of OA symptoms, including lameness, weight-bearing, pain response, and clinical OA scores. a Lameness score in the affected knees of dogs. b Weight-bearing score. c Severity of pain response. d Clinical OA scores. The arrow indicates the time point of intra-articular injection (6 weeks) of normal saline (Control) or target cells. *P < 0.05 and **P < 0.01 compared to the control at specific time points. #P < 0.05 and ##P < 0.01 compared to before treatment within groups

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