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Table 3 Subgroup analysis of FIB for PJI diagnosis

From: Reliability of circulating fibrinogen in the diagnosis of prosthesis-related infections: a systematic review and meta-analysis

Subgroup No. of studies Sensitivity (95% CI) Specificity (95% CI) PLR (95% CI) NLR (95% CI) DOR (95% CI) AUC
Plasma FIB 5 0.74 (0.69–0.79) 0.83 (0.81–0.86) 4.51 (3.14–6.47) 0.29 (0.22–0.38) 17.85 (12.71–25.07) 0.8945
China 6 0.75 (0.70–0.79) 0.84 (0.81–0.86) 4.84 (3.31–7.09) 0.28 (0.21–0.36) 19.56 (13.46–28.43) 0.8880
  1. FIB fibrinogen, CI confidence interval, PLR positive likelihood ratio, NLR negative likelihood ratio, DOR diagnostic odds ratio, AUC area under the curve