Table 1 Blood loss and Surgery time of included studies
Study | High dose tranexamic acid | Control/placebo | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
No. of patient | Blood loss (mL) | SD | Surgery time (h) | SD | No. of patient | Blood loss (mL) | SD | Surgery time (h) | SD | |
Ng et al. [10] | 55 | 1826.11 | 1081.45 | 7.28 | 2.04 | 35 | 3889.6 | 2440.8 | 8.36 | 1.4 |
da Rocha et al. [11] | 21 | 1097.3 | 323.9 | 4 | 1.2 | 19 | 1406.5 | 372.1 | 4.3 | 1.4 |
Sethna et al. [12] | 23 | 1072 | 425 | 6.6 | 1.8 | 21 | 1420 | 644 | 6.1 | 1.8 |
Lykissas et al. [13] | 25 | 537 | 320 | NR | NR | 24 | 1245 | 896 | NR | NR |
Goobie et al. [14] | 56 | 836 | 373 | 4.5 | 1.2 | 55 | 1031 | 484 | 4.2 | 0.96 |