From: Investigating the molecular control of deer antler extract on articular cartilage
Gene name | Expression level (FPKM) | log2 fold change (DAE/Blank) | p value | |
---|---|---|---|---|
Blank | DAE | |||
Hyaluronan and proteoglycan link protein 1 (Hapln1) | 301.97 | 901.64 | 1.58 | 0 |
Collagen alpha-1(IX) chain (Col9a1) | 142.16 | 519.76 | 1.87 | 0 |
Scrapie-responsive protein 1 (Scrg1) | 203.52 | 491.32 | 1.27 | 1.23E−92 |
Cartilage oligomeric matrix protein (Comp) | 230.34 | 490.17 | 1.09 | 0 |
Leukocyte cell-derived chemotaxin 1 (Cnmd) | 135.34 | 397.34 | 1.55 | 1.08e−321 |
Carbonic anhydrase 2 (Ca2) | 172.19 | 352.43 | 1.03 | 2.61E−159 |
Matrilin-3 (Matn3) | 112.11 | 292.66 | 1.38 | 0 |
Transferrin receptor protein 1 (Tfrc) | 46.77 | 117.84 | 1.33 | 1.65E−274 |
Vascular endothelial growth factor A (Vegfa) | 51.06 | 107.19 | 1.07 | 8.57E−143 |
Collagen alpha-1(XXVII) chain (Col27a1) | 41.63 | 90.66 | 1.12 | 2.44E−248 |
M-phase inducer phosphatase 2 (Cdc25b) | 33.93 | 76.00 | 1.16 | 1.82E−92 |
Proliferation marker protein Ki-67 (Mki67) | 21.76 | 45.38 | 1.06 | 6.36E−136 |
Carbonic anhydrase 12 (Ca12) | 10.53 | 35.95 | 1.77 | 2.03E−95 |
Radical S-adenosyl methionine domain-containing protein 2 (Rsad2) | 9.91 | 29.91 | 1.59 | 1.27E−69 |
T cell acute lymphocytic leukemia protein 1 homolog (Tal1) | 10.64 | 23.50 | 1.14 | 2.07E−44 |
Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (Csgalnact1) | 11.15 | 22.80 | 1.03 | 3.03E−18 |
Cartilage matrix protein (Matn1) | 4.78 | 21.71 | 2.18 | 3.49E−40 |
Chordin-like protein 1 (Chrdl1) | 7.49 | 19.15 | 1.35 | 2.56E−41 |
Thrombospondin-3 (Thbs3) | 5.25 | 16.71 | 1.67 | 7.21E−37 |
Complement decay-accelerating factor, GPI-anchored (Cd55) | 7.74 | 15.89 | 1.04 | 1.04E−10 |
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Bub1) | 7.32 | 14.81 | 1.02 | 4.70E−23 |
G1/S-specific cyclin-E2 (Ccne2) | 6.42 | 14.00 | 1.12 | 1.48E−17 |
Protein MGARP (Mgarp) | 4.50 | 12.66 | 1.49 | 1.12E−09 |
M-phase phosphoprotein 8 (Mphosph8) | 5.78 | 12.46 | 1.11 | 2.24E−14 |
Noggin (Nog) | 4.80 | 11.69 | 1.28 | 7.67E−10 |
Carbonic anhydrase 9 (Ca9) | 5.45 | 11.63 | 1.09 | 7.97E−10 |
ESF1 homolog (Esf1) | 5.27 | 11.61 | 1.14 | 1.35E−16 |
Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Arntl) | 3.14 | 10.98 | 1.81 | 2.48E−25 |
H(+)/Cl(-) exchange transporter 3 (Clcn3) | 4.15 | 9.18 | 1.15 | 1.12E−08 |
G2/M phase-specific E3 ubiquitin-protein ligase (G2e3) | 3.80 | 7.66 | 1.01 | 2.15E−13 |
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (Dyrk3) | 2.45 | 6.59 | 1.43 | 7.06E−09 |
Protein kinase C zeta type (Prkcz) | 2.98 | 6.32 | 1.08 | 5.86E−07 |
WNT1-inducible-signaling pathway protein 3 (Wisp3) | 2.82 | 5.89 | 1.06 | 2.27E−06 |
Centrosomal protein of 70 kDa (Cep70) | 2.02 | 4.72 | 1.22 | 2.28E−08 |
Dermatopontin (Dpt) | 1.46 | 3.97 | 1.44 | 3.09E−07 |
Murinoglobulin-1 (Mug1) | 0.56 | 1.67 | 1.58 | 3.76E−06 |