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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Naringin increases osteoprotegerin expression in fibroblasts from periprosthetic membrane by the Wnt/β-catenin signaling pathway

Fig. 3

Naringin stimulated OPG secretion by periprosthetic membrane-derived fibroblasts. The fibroblasts were treated with naringin at various concentrations (50 μM, 100 μM, 150 μM) or in medium alone (control group) for 24 h. The levels of a RANKL and b OPG in the supernatant were determined by ELISA. Naringin did not increase RANKL secretion but enhanced OPG secretion in a dose-dependent manner (ap < 0.01, bp < 0.001)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X