Variables | N (study) | N (THA) | N (HA) | Pooled data | Heterogeneity | ||
---|---|---|---|---|---|---|---|
WMD/RR(95%CI) | P | I2(%) | Ph | ||||
Hospital and Surgery | |||||||
 Hospital length | 9 | 418 | 443 | 2.360 (0.215, 4.506) | 0.031 | 96.0% | < 0.0001 |
 Hospital length (deleted Li et al. [25], Liu et al. [27]) | 7 | 324 | 349 | 0.721 (0.362, 1.080) | < 0.0001 | 0% | 0.428 |
 Surgery time | 15 | 1292 | 1341 | 20.044 (14.257, 25.830) | < 0.0001 | 95.7% | < 0.0001 |
 Blood loss | 9 | 1063 | 1038 | 69.106 (39.083, 99.129) | < 0.0001 | 96.4% | < 0.0001 |
 Blood loss (deleted developing countries’ studies) | 4 | 881 | 856 | 76.027 (51.951, 100.104) | < 0.0001 | 17.6% | 0.303 |
Clinical outcomes | |||||||
 By follow-up |  |  |  |  |  |  |  |
  HHS(< 6 months) | 5 | 208 | 208 | 1.641 (− 0.449, 3.731) | 0.124 | 0% | 0.784 |
  HHS (at 1 year) | 6 | 317 | 333 | 3.593 (1.278, 5.907) | 0.002 | 12.5% | 0.335 |
  HHS (at 2 years) | 5 | 174 | 168 | 3.691 (0.571, 6.812) | 0.020 | 38.8% | 0.162 |
  HHS (3 to 5 years) | 5 | 233 | 251 | 6.027 (0.434, 11.621) | 0.035 | 90.1% | < 0.0001 |
  HHS (at 9 years) | 2 | 57 | 71 | 5.848 (− 4.603, 16.299) | 0.273 | 74.1% | 0.050 |
  Pain (HHS subscore) | 3 | 148 | 148 | 0.065 (− 0.385, 0.515) | 0.777 | 85.5% | < 0.0001 |
  Pain (HHS subscore, < 6 months) | 2 | 97 | 97 | − 0.042 (− 0.686, 0.602) | 0.897 | 79.5% | 0.027 |
  Pain (HHS subscore, at 1 year) | 3 | 128 | 128 | 0.405(− 0.575, 1.385) | 0.418 | 92.7% | 0.000 |
  Pain (HHS subscore, at 2 years) | 2 | 57 | 57 | − 0.020 (− 0.902, 0.862) | 0.964 | 78.6% | 0.031 |
  EQ-5D(<6 months) | 3 | 183 | 214 | 0.031 (− 0.031, 0.093) | 0.324 | 2.1% | 0.360 |
  EQ-5D(at 1 year) | 3 | 181 | 177 | 0.033 (− 0.036, 0.102) | 0.351 | 0.0% | 0.951 |
  EQ-5D(at 2 years) | 3 | 173 | 165 | 0.107 (0.049, 0.164) | < 0.0001 | 0.0% | 0.525 |
  Pain (binary) | 3 | 827 | 783 | 0.244 (0.050, 1.183) | 0.080 | 91.0% | < 0.0001 |
Common complications | |||||||
 Pulmonary embolism | 4 | 187 | 235 | 0.597 (0.158, 2.257) | 0.447 | 0% | 0.517 |
 Deep vein thrombosis | 8 | 397 | 439 | 1.004 (0.386, 2.614) | 0.994 | 13.3% | 0.326 |
 Pneumonia | 7 | 308 | 315 | 0.932 (0.431, 2.014) | 0.858 | 0% | 0.733 |
 Pressure injury | 4 | 183 | 185 | 1.233 (0.301, 5.056) | 0.771 | 0% | 0.516 |
 Wound disease | 10 | 1170 | 1227 | 0.857 (0.488, 1.505) | 0.591 | 0% | 0.933 |
 Surgical site infection | 5 | 967 | 974 | 0.963 (0.422, 2.200) | 0.929 | 17.3% | 0.305 |
 Cardiovascular disease | 6 | 286 | 335 | 1.474 (0.672, 3.233) | 0.333 | 0% | 0.669 |
Implant-related complications | |||||||
 Revision | 13 | 1397 | 1480 | 0.736 (0.419, 1.292) | 0.286 | 47.2% | 0.030 |
12 | 1308 | 1389 | 0.882 (0.513, 1.517) | 0.651 | 30.3% | 0.150 | |
 Fracture | 7 | 1065 | 1094 | 1.064 (0.707, 1.600) | 0.767 | 0% | 0.853 |
 Dislocation | 16 | 1473 | 1562 | 1.897 (1.273, 2.827) | 0.002 | 4% | 0.407 |
 Heterotopic Ossification | 3 | 853 | 880 | 1.272 (0.844, 1.918) | 0.251 | 0% | 0.647 |
 Loosening or Subsidence | 2 | 833 | 860 | 0.640 (0.170, 2.409) | 0.509 | 25.5% | 0.247 |
 Acetabular Erosion | 2 | 215 | 238 | 0.030 (0.004, 0.219) | 0.001 | 0% | 0.769 |
Mortality | |||||||
 By follow-up |  |  |  |  |  |  |  |
  Mortality (in hospital) | 8 | 414 | 456 | 1.484 (0.616, 3.579) | 0.379 | 0% | 0.434 |
  Mortality (< 6 months) | 2 | 69 | 76 | 0.679 (0.094, 4.892) | 0.767 | 37.5% | 0.206 |
  Mortality (at 1 year) | 7 | 372 | 394 | 1.011 (0.684, 1.493) | 0.958 | 0% | 0.705 |
Mortality (at 2 years) | 8 | 1197 | 1294 | 1.224(1.055,1.421) | 0.008 | 12.3% | 0.334 |
Mortality(3 to 5 years) | 2 | 249 | 270 | 1.138(0.869,1.490) | 0.346 | 12.8% | 0.284 |
Mortality(9 to 13 years) | 3 | 435 | 473 | 1.021(0.881,1.183) | 0.786 | 0% | 0.489 |