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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: miR-107 affects cartilage matrix degradation in the pathogenesis of knee osteoarthritis by regulating caspase-1

Fig. 1

Effects of LPS/ATP induction on chondrocytes. a The proliferation of chondrocytes treated with LPS and ATP was detected by CCK-8 assay. *P < 0.05 and ***P < 0.001 vs. control group. #P < 0.05 and ###P < 0.001 vs. LPS group. b The expression of Col II in supernatant of chondrocytes treated with LPS and ATP was detected by Col II ELISA assay. **P < 0.01 and ***P < 0.001 vs. control group. ##P < 0.01 vs. LPS group. c The expression of IL-1β in supernatant of chondrocytes treated with LPS and ATP was detected by IL-1β ELISA assay. ***P < 0.001 vs. control group. ###P < 0.001 vs. LPS group. d The expression of IL-18 in supernatant of chondrocytes treated with LPS and ATP was detected by IL-18 ELISA assay. **P < 0.01 and ***P < 0.001 vs. control group. ###P < 0.001 vs. LPS group. e The expression of MMP-13 in supernatant of chondrocytes treated with LPS and ATP was detected by MMP-13 ELISA assay. ***P < 0.001 vs. control group. ###P < 0.001 vs. LPS group. f miR-107 expression in chondrocytes treated with LPS and ATP was analyzed by RT-qPCR analysis. *P < 0.05 and ***P < 0.001 vs. control group. ##P < 0.01 vs. LPS group

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X