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Table 5 Methodological quality of included studies

From: Intra-articular vs. intravenous administration: a meta-analysis of tranexamic acid in primary total knee arthroplasty

Study Quality score Random generation sequence Allocation concealment Blind Incomplete outcome data Selective reporting Other biases
Jules-Elysee et al. [14] 7 Computer-generated randomization schedule Unclear Yes No No No
Laoruengthana et al. [13] 8 Computer-generated numbers Concealed envelope Yes No No No
Zhang et al. [15, 52] 8 Randomized numbers table Labeled with numbering code Yes No No No
Abdel et al. [20] 6 Randomized but unknown method Unclear Yes No No No
Ahmed et al. [17] 6 The lottery method Unclear No No No No
López-Hualda et al [21] 5 Randomized but unknown method Unclear No No No No
George et al. [16] 8 Computer-generated numbers Concealed envelope Yes No No No
Subramanyam et al. [19] 8 Computer-generated numbers Concealed envelope Yes No No No
Wei et al. [18] 8 Randomized numbers table Concealed envelope Yes No No No
Goyal et al. [36] 8 Computer-generated numbers Concealed envelope Yes No No No
Lacko et al. [22] 6 Computer-generated numbers Unclear No No No No
Maniar et al. [33] 8 Randomly drawing sealed envelope from container Concealed envelope Yes No No No
Prakash et al. [26] 7 Randomized but unknown method Concealed envelope Yes No No No
Song et al. [35] 8 Computer-generated numbers Concealed envelope Yes No No No
Stowers et al. [24] 8 Block randomization Concealed envelope Yes No No No
Uğurlu et al. [34] 5 Randomized but unknown method Unclear No No No No
Wang et al. [11, 23] 8 Randomly drawing sealed envelope from container Concealed envelope Yes No No No
Zekcer et al. [25] 8 Randomly drawing sealed envelope from container Concealed envelope Yes No No No
Aggarwal et al. [39] 8 Computer-generated numbers Concealed envelope Yes No No No
Chen et al. [29, 53] 8 Randomized numbers table Concealed envelope Yes No No No
Drosos et al. [38] 8 Stratified randomization by minimization Concealed envelope Yes No No No
Keyhani et al. [42] 5 Randomized but unknown method Unclear No No No No
May et al. [37] 7 Randomized numbers table Unclear Yes No No No
Pinsornsak et al. [37] 7 Randomized but unknown method Concealed envelope Yes No No No
Tzatzairis et al. [40] 6 Stratified randomization by minimization Unclear No No No No
Aguilera et al. [43] 7 Randomized numbers table Unclear Yes No No No
Digas et al. [44] 7 Randomized but unknown method Concealed envelope Yes No No No
Öztaş et al. [45] 5 Randomized but unknown method Unclear No No No No
Gomez-Barrena et al. [46] 7 Randomized but unknown method Concealed envelope Yes No No No
Patel et al. [47] 7 Excel’s randomization Unclear Yes No No No
Sarzaeem et al. [48] 7 Randomized numbers table Unclear Yes No No No
Soni et al. [49] 6 Computer-generated numbers Unclear No No No No
Seo et al. [50] 7 Randomized numbers table Unclear Yes No No No
Maniar et al. [51] 8 Randomly drawing sealed envelope from container Concealed envelope Yes No No No