Fig. 1

Hierarchical cluster of miRNAs. HBO modulates the expression of miRNAs in degenerated NP cells. a A heat map of the miRNAs with significantly changed expression levels in the HBO-treated group compared with the control group. Average expression value is shown for each miRNA in each class. The red and green colors indicate that the ΔCt value is below (relatively high expression) and above (relatively low expression levels) the median of all ΔCt values. b MiR-573 was chosen for further investigation. c HBO treatment increased miR-573 expression in NP cells (*p < 0.05)