Fig. 3

CPEB1 regulates chondrocyte viability and apoptosis. After OA modeling, chondrocytes were transfected with si-CPEB1 or pcDNA3.1-CPEB1; mRNA and protein expression levels of CPEB1 were detected by qRT-PCR and Western blot (a, b); the role of CPEB1 in chondrocyte viability (c), apoptosis (d), and cleaved caspase-3 expression (e) were measured. *P < 0.05, **P < 0.01 compared to the sham group; @ P < 0.05 compared to the si-NC group; #P < 0.05 compared to the OA + si-NC group; &P < 0.05 compared to the OA + pcDNA3.1 group. OA, osteoarthritis