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Table 2 Comparison of the clinical characteristics, preoperative laboratory values, and perioperative data among the 3 groups stratified by the grade of blood loss, as determined by the ATLS hypovolemic shock classification system

From: Factors associated with blood loss in ankylosing spondylitis patients with hip involvement undergoing primary total hip arthroplasty: a cross-sectional retrospective study of 243 patients

 

Grade of blood loss

P value

I < 750 ml (n = 49)

II 750~1500 ml (n = 121)

III> 1500 ml (n = 73)

Clinical characteristics

 Age (years)

32 (19 to 67)

32 (19 to 59)

34 (22 to 53)

0.449 c

 Male (n, %)

37 (75.5%)

110 (90.9%)

71 (97.3%)

< 0.0001a

 BMI (kg/m2)

21.83 (11.87 to 36.73)

22.76(15.06 to 36.98)

23.39 (15.22 to 37.11)

0.078 c

 Disease duration (years)

10 (0.5 to 40.3)

10.5 (1.0 to 30.0)

14 (0.5 to 34)

0.114 c

 Bilateral THA (n, %)

8 (16.3%)

84 (69.4%)

71 (97.3%)

< 0.0001a

 Hip ROM = 0° (n, %)

10 (20.4%)

60 (49.6%)

51 (69.9%)

< 0.0001a

 BASRI-hip score of 4 (n, %)

16 (32.7%)

68 (56.2%)

55 (75.3%)

< 0.0001a

Preoperative laboratory values

 Elevated level of ESR (n, %)

23(46.9%)

75(62.0%)

34(46.6%)

0.058a

 Elevated level of CRP (n, %)

31 (63.3%)

89 (73.6%)

45 (61.6%)

0.168a

 TT (s)

15.7 ± 0.8

16.2 ± 1.0

16.2 ± 1.0

0.013b

 APTT (s)

40.6 ± 4.8

41.4 ± 4.7

38.7 ± 4.9

0.001b

 PT (s)

13.6 ± 0.8

13.5 ± 0.8

13.4 ± 0.9

0.206b

 PT (%)

93.2 ± 11.3

93.9 ± 11.9

96.1 ± 12.7

0.346b

 INR

1.06 ± 0.08

1.05 ± 0.08

1.03 ± 0.08

0.219b

 Fibrinogen level (g/L)

4.04 (2.42 to 7.41)

4.45 (1.90 to 13.10)

4.06 (1.76 to 6.16)

0.014c

 Platelet level (× 109/L)

270 ± 67

289 ± 77

249 ± 58

0.001b

 Hb level (g/L)

127 ± 15

131 ± 16

140 ± 16

< 0.0001b

 Hct (L/L)

0.386 ± 0.041

0.401 ± 0.042

0.423 ± 0.041

< 0.0001b

Perioperative data

 Iliopsoas and adductor release (n, %)

2 (4.1%)

23 (19.0%)

16 (21.9%)

0.024a

 Administration of TXA (n, %)

40 (81.6%)

77 (63.6%)

42 (57.5%)

< 0.0001a

 Chemoprophylaxis of thrombosis (n, %)

30(61.2%)

97(80.2%)

56(76.7%)

0.033a

 Operating time (min)

100 (55 to 250)

180 (60 to 335)

210 (70 to 455)

< 0.0001c

 Autologous transfusion (n, %)

3 (6.1%)

30 (24.8%)

33 (45.2%)

< 0.0001a

 Allogenic transfusion (n, %)

37 (75.5%)

119 (98.3%)

73 (100%)

N/A

 ASA class

   

0.672a

  1

5

6

4

 

  2

40

105

65

 

  3

4

10

4

 
  1. ATLS Advanced Trauma Life Support, AS ankylosing spondylitis, THA total hip arthroplasty, BMI body mass index, ROM range of motion, BASRI-hip Bath Ankylosing Spondylitis Radiology Hip Index, ESR erythrocyte sedimentation rate, CRP C-reactive protein, TT thromboplastin time, APTT activated partial thromboplastin time, PT prothrombin time, PT% prothrombin activity, INR international normalized ratio, Hb hemoglobin, Hct hematocrit, TXA tranexamic acid, ASA American Society of Anesthesiologists
  2. aChi-square test
  3. bOne-way ANOVA
  4. cWilcoxon rank sum test