| |
ADACI
|
Statistics
|
|---|
|
Yes (n = 50)
|
No (n = 324)
|
χ2
|
p value
|
z score
|
Crude OR
|
95% CI
|
p value
|
|---|
|
Demographics
|
|
Age (years)
|
73.3 ± 8.4
|
69.4 ± 9.0
|
-
|
0.004
|
-
|
1.05
|
1.02–1.09
|
0.005
|
|
Male
|
35 (70%)
|
167 (51.5%)
|
5.94
|
0.015
|
2.4
|
2.19
|
1.15–4.17
|
0.020
|
|
Female
|
15 (30%)
|
157 (48.5%)
|
5.94
|
0.015
|
-2.4
|
0.46
|
0.24–0.87
|
0.020
|
|
BMI
|
31.4 ± 5.9
|
31.2 ± 5.3
|
-
|
0.880
|
-
|
1.01
|
0.95–1.06
|
0.870
|
|
Past medical Hx
|
|
Diabetes
|
9 (18%)
|
47 (14.5%)
|
0.42
|
0.519
|
0.6
|
1.30
|
0.59–2.84
|
0.520
|
|
Hypertension
|
37 (74%)
|
207 (63.9%)
|
1.95
|
0.162
|
1.4
|
1.61
|
0.82–3.15
|
0.170
|
|
Hypercholesterolaemia
|
30 (60.0%)
|
186 (57.4%)
|
0.12
|
0.730
|
0.3
|
1.11
|
0.61–2.04
|
0.730
|
|
Smoking
|
6 (12.0%)
|
16 (4.9%)
|
9.52
|
0.009
|
2.0
|
3.39
|
1.22–9.42
|
0.020
|
|
Ex-smoker
|
18 (36.0%)
|
73 (22.5%)
|
9.52
|
0.009
|
2.1
|
2.23
|
1.16–4.29
|
0.020
|
|
Alcohol
|
6 (12.0%)
|
36 (11.1%)
|
0.03
|
0.853
|
0.2
|
1.09
|
0.43–2.74
|
0.850
|
|
Asthma
|
7 (14.0%)
|
37 (11.4%)
|
0.28
|
0.598
|
0.5
|
1.26
|
0.53–3.01
|
0.600
|
|
COPD
|
2 (4.0%)
|
12 (3.7%)
|
0.01
|
0.918
|
0.1
|
1.08
|
0.24–4.99
|
0.920
|
|
OSA
|
4 (8.0%)
|
39 (12.0%)
|
0.69
|
0.405
|
-0.8
|
0.64
|
0.22–1.86
|
0.410
|
|
Past CV Hx
|
|
Cardiac Hx total
|
16 (32%)
|
116 (35.8%)
|
0.27
|
0.601
|
-0.5
|
0.84
|
0.45–1.59
|
0.600
|
|
CCF
|
0 (0.0%)
|
8 (2.5%)
|
1.26
|
0.261
|
-1.1
|
0.37
|
0.02–6.49
|
0.500
|
|
MI
|
6 (12.0%)
|
22 (6.8%)
|
1.70
|
0.193
|
1.3
|
1.87
|
0.72–4.87
|
0.200
|
|
CAD
|
11 (22%)
|
63 (19.4%)
|
0.18
|
0.673
|
0.4
|
1.14
|
0.56–2.34
|
0.710
|
|
Valvular disease
|
5 (10.0%)
|
20 (6.2%)
|
1.02
|
0.313
|
1.0
|
1.69
|
0.60–4.73
|
0.320
|
|
Arrhythmia
|
6 (12.0%)
|
49 (15.1%)
|
0.34
|
0.562
|
-0.6
|
0.79
|
0.32–1.94
|
0.610
|
|
PVD
|
2 (4.0%)
|
5 (1.5%)
|
1.42
|
0.233
|
1.2
|
2.66
|
0.50–14.09
|
0.250
|
|
CVA
|
8 (16.0%)
|
19 (5.9%)
|
6.64
|
0.010
|
2.6
|
2.45
|
1.04–5.74
|
0.040
|
|
VTE
|
4 (8.0%)
|
10 (3.1%)
|
2.90
|
0.088
|
1.7
|
2.73
|
0.82–9.07
|
0.100
|
|
CKD
|
3 (6.0%)
|
20 (6.2%)
|
0.47
|
0.790
|
0.0
|
0.97
|
0.28–3.37
|
0.970
|
|
Family Hx of cardiac disease
|
16 (32.0%)
|
56 (17.3%)
|
6.03
|
0.014
|
2.5
|
2.25
|
1.16–4.36
|
0.020
|
|
Baseline cardiac Ix
|
|
ECG abnormality
|
24 (48.0%)
|
91 (28.1%)
|
8.07
|
0.005
|
2.8
|
2.36
|
1.29–4.33
|
0.005
|
|
Ejection fraction (%)
|
58.9 ± 11.6
|
64.6 ± 7.3
|
-
|
0.002
|
-
|
0.93
|
0.89–0.96
|
<0.001
|
- Numerical predictor variables (age, BMI, ejection fraction) are presented as mean ± standard deviation and were assessed using an independent t test. Categorical predictor variables are presented as frequencies and were assessed using chi-squared test of independence. The crude ratio and associated 95% CI are also reported. Significant predictor variables are indicated by p < 0.05
- ADACI abnormality detected upon additional cardiac investigation, OR odds ratio, BMI body mass index, CV cardiovascular, Hx history, CCF chronic heart failure, MI myocardial infarction, CAD coronary artery disease, PVD peripheral vascular disease, CVA cerebrovascular accident, VTE venous thromboembolism, CKD chronic kidney disease, COPD chronic obstructive pulmonary disease, OSA obstructive sleep apnoea, Ix investigation, ECG electrocardiogram
