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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Knockdown of long non-coding RNA LEF1-AS1 attenuates apoptosis and inflammatory injury of microglia cells following spinal cord injury

Fig. 2

Knockdown of lncRNA LEF-AS1 could decrease the LPS-induced microglia cells apoptosis. a The expression level of lncRNA LEF-AS1 in si-NC and si-LEF-AS1 groups. b Cell viability in LPS and/or transfected with si-LEF-AS1. c Apoptosis ratio in LPS and/or transfected with si-LEF-AS1 measured by Annexin V/FITC apoptosis assay. d Western blot assay measuring protein expression of apoptotic markers (Bax, Bcl-2, and cleaved-caspase-3) in microglia cells transfected with si-LEF-AS1. e Inflammatory cytokines (TNF-α and IL-6) expression levels in microglia cells transfected with si-LEF-AS1. *P < 0.05

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X