Fig. 1
From: Outcome of lung metastases due to bone giant cell tumor initially managed with observation
Diagram of patient outcomes. a Progression ceased in two patients (case 6, 17). b One of these two patients received chemotherapy before starting denosumab treatment and lung lesions progressed under chemotherapy (case 12). c One of these patients received a second metastasectomy due to slow progression and never experienced recurrence (case 14), and the other patient received a metastasectomy three more times due to slow progression and never experienced recurrence (case 15). d This patient had a lung lesion with slow progression (case 9). e One of these 3 patients experienced recurrence and received stereotactic radiotherapy and the lung lesion regressed (case 5), while another patient experienced recurrence and underwent metastasectomy, and no further recurrence was observed (case 10). f These two patients experienced recurrences (case 3, 11). g Progression ceased in this patient. NED, no evidence of disease; AWD, alive with disease