Plasma total homocysteine quartiles (μmol/L) | Q1 (5-6.86) | Q2 (6.87-8.22) | Q3 (8.23-9.95) | Q4 (9.96-15) | P value |
---|---|---|---|---|---|
Age (years) | 44.31 ± 10.71 | 47.24 ± 11.86 | 50.15 ± 12.76 | 55.27 ± 14.31 | <0.001 |
Gender (%) | <0.001 | ||||
Male | 31.07 | 48.73 | 61.36 | 65.57 | |
Female | 68.93 | 51.27 | 38.64 | 34.43 | |
Race (%) | <0.001 | ||||
Non-Hispanic White | 66.75 | 73.54 | 75.27 | 76.86 | |
Non-Hispanic Black | 10.76 | 10.33 | 10.58 | 10.82 | |
Mexican American | 9.35 | 6.82 | 5.02 | 3.95 | |
Other race | 13.13 | 9.31 | 9.13 | 8.37 | |
Body mass index (kg/m2) | 28.31 ± 6.70 | 28.86 ± 6.49 | 28.60 ± 5.90 | 28.81 ± 6.03 | 0.004 |
Education level (%) | <0.001 | ||||
Less than high school | 18.49 | 17.68 | 18.73 | 22.24 | |
High school | 22.56 | 25.37 | 26.40 | 28.40 | |
More than high school | 58.95 | 56.96 | 54.88 | 49.36 | |
Income-poverty ratio | 3.19 ± 1.56 | 3.27 ± 1.52 | 3.26 ± 1.54 | 3.04 ± 1.53 | <0.001 |
Physical activity (%) | <0.001 | ||||
Not walk very much | 14.66 | 15.03 | 15.84 | 19.79 | |
Walk a lot | 27.89 | 27.38 | 26.34 | 27.87 | |
Climb often | 21.30 | 20.47 | 17.30 | 15.48 | |
Heavy activity | 30.60 | 31.00 | 32.64 | 28.28 | |
Not recorded | 5.54 | 6.13 | 7.88 | 8.58 | |
Smoking behavior (%) | <0.001 | ||||
None | 57.23 | 51.12 | 46.64 | 41.37 | |
Past | 22.45 | 26.51 | 28.00 | 29.13 | |
Current | 20.32 | 22.36 | 25.35 | 29.50 | |
Alcohol consumption (%) | <0.001 | ||||
Non-drinker | 33.22 | 32.40 | 29.99 | 36.10 | |
Moderate alcohol use | 41.36 | 35.15 | 33.15 | 30.16 | |
High alcohol use | 25.42 | 32.45 | 36.86 | 33.74 | |
Blood urea nitrogen (mg/dL) | 12.39 ± 3.81 | 12.99 ± 3.92 | 13.69 ± 4.32 | 14.57 ± 5.65 | <0.001 |
Total protein (mg/dL) | 7.25 ± 0.46 | 7.26 ± 0.46 | 7.29 ± 0.46 | 7.31 ± 0.50 | <0.001 |
Total cholesterol (mg/dL) | 201.1 ± 37.3 | 205.8 ± 40.2 | 210.1 ± 42.1 | 210.4 ± 45.9 | <0.001 |
Serum uric acid (mg/dL) | 4.81 ± 1.20 | 5.30 ± 1.30 | 5.59 ± 1.32 | 6.01 ± 1.39 | <0.001 |
Serum folate (ng/mL) | 15.75 ± 10.20 | 14.82 ± 15.76 | 14.07 ± 11.01 | 13.04 ± 9.07 | <0.001 |
Serum vitamin B12( pg/mL) | 611.6 ± 1758.3 | 534.8 ± 314.4 | 490.0 ± 240.1 | 450.8 ± 299.7 | <0.001 |
Serum phosphorus (mg/dL) | 3.63 ± 0.53 | 3.67 ± 0.56 | 3.68 ± 0.56 | 3.68 ± 0.57 | 0.002 |
Serum calcium (mg/dL) | 9.39 ± 0.35 | 9.46 ± 0.36 | 9.52 ± 0.35 | 9.57 ± 0.38 | <0.001 |
Lumbar bone mineral density (g/cm2) | 1.05 ± 0.15 | 1.04 ± 0.15 | 1.04 ± 0.16 | 1.04 ± 0.17 | 0.054 |