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Table 5 Baseline characteristics and intraoperative and postoperative outcomes

From: Hemostatic effect of tourniquet combined with tranexamic acid in total knee arthroplasty: a network meta-analysis

Group IV TXA TopicalTXA IV-combined topical TXA OralTXA Placebo + tourniquets IV TXA + tourniquets Topical TXA + tourniquets IV-combined topical \TXA + tourniquets P value
Number 30 30 30 30 30 30 30 30  
Age(y) 67.77 ± 5.39 67.37 ± 5.49 66.73 ± 6.15 66.3 ± 4.89 65.23 ± 6.28 65.73 ± 5.99 67.13 ± 5.56 65.43 ± 4.78 0.532
Gender(female/male) 16/14 20/10 21/9 15/15 18/12 16/14 22/8 21/9 0.394
BMI(kg/m2) 30.05 ± 3.02 30.43 ± 4.28 30.72 ± 2.93 30.54 ± 3.09 29.49 ± 3.87 29.62 ± 3.37 31.41 ± 3.62 31.33 ± 4.11 0.307
Preop.ROM(°) 99.87 ± 8.33 100.01 ± 7.83 103.45 ± 5.35 101.53 ± 6.28 102.08 ± 6.72 99.37 ± 5.04 100.88 ± 6.98 102.41 ± 7.73 0.238
Surgical duration(min) 67.60 ± 12.39 64.93 ± 10.79 68.13 ± 8.97 66.03 ± 12.17 66.07 ± 9.75 64.00 ± 8.53 63.37 ± 12.18 70.10 ± 11.18 0.256
Total blood loss(mL) 1268.84 ± 342.15 1164.27 ± 304.19 653.79 ± 246.20 781.26 ± 213.79 1584.33 ± 359.21 1049.12 ± 266.72 1002.48 ± 316.29 739.15 ± 226.37 <0.001
Transfusion 9 5 1 7 12 3 5 4 0.009*
Preop.Hb(g/dL) 13.87 ± 0.66 13.44 ± 1.23 13.92 ± 1.25 13.89 ± 0.95 13.62 ± 1.02 13.41 ± 1.07 13.99 ± 1.09 13.47 ± 0.72 0.117
24-h Hb(g/dL) 11.82 ± 1.04 11.49 ± 1.30 12.09 ± 1.40 12.74 ± 0.94 10.37 ± 1.26 11.48 ± 1.35 11.94 ± 1.31 12.11 ± 0.95 <0.001*
Hb change(g/dL) 2.02 ± 0.84 1.95 ± 0.57 1.83 ± 0.61 1.14 ± 0.39 3.22 ± 1.06 1.93 ± 0.75 2.09 ± 0.61 1.36 ± 0.55 <0.001*
DVT 1 0 0 0 0 1 0 0 0.541
PE 0 0 0 0 0 0 1 0 0.432
  1. Notes: Preop.ROM preoperative range of motion, Preop.Hb preoperative hemoglobin. Measurement data are presented as mean ± standard deviation. Comparisons among multiple groups were analyzed using ANOVA, followed by Tukey’s post hoc test. Enumeration data were analyzed by chi-square test. *p < 0.05