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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Galuteolin suppresses proliferation and inflammation in TNF-α-induced RA-FLS cells by activating HMOX1 to regulate IKKβ/NF-κB pathway

Fig. 4

Silence of HO-1 weakened the effects of galuteolin on inflammation response of RA-FLS cells. a The mRNA expression of IL-1β, IL-6, IL-8, and MMP-1 was detected after indicated treatments and HO-1 siRNA transfection in RA-FLS cells by RT-qPCR. b The levels expression of IL-1β, IL-6, IL-8, and MMP-1 were detected after indicated treatments and HO-1 siRNA transfection in RA-FLS cells by ELISA. *p < 0.05 vs. Galu; #p < 0.05 and ##p < 0.01 and ###p < 0.001 vs. Galu + TNF-α

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X