Table 1 General information of included studies
Author (year) | Country | Age (year) (AIS/control) | BMI (kg/m2) (AIS/control) | No of case (AIS/control) | Leptin (ng/ml) (AIS/Control) | sOB-R (ng/ml) (AIS/Control) | Free leptin index (Leptin/sOB-R) (AIS/Control) | Ghrelin (pg/ml) (AIS/control) | Detection method |
|---|---|---|---|---|---|---|---|---|---|
Qiu et al. 2007 [11] | China | 13.5/15.1 | 17.5 ± 0.2/20.9 ± 0.4 | 47/80 | 8.6 ± 0.8/14.9 ± 0.9 | ELISA | |||
Liu et al. 2012 [12] | China | 13.7 ± 1.5/13.8 ± 1.4 | 17.8 ± 2.3/19.5 ± 2.2 | 95/46 | 7.0 ± 5.0/8.4 ± 5.8 | 23.7 ± 6.7/20.5 ± 5.6 | 0.33 ± 0.25/0.48 ± 0.41 | ELISA | |
Clark 2014 [23] | UK | None | 17.2 ± 2.9/17.6 ± 2.8 | 180/3152 | 5.24 ± 4.26/6.28 ± 5.11 | ELISA | |||
Tam et al. 2014 [18] | China | 13.05 ± 0.52/12.93 ± 0.43 | 17.91 ± 2.20/18.64 ± 2.15 | 94/87 | 6.75 ± 5.01/7.26 ± 4.99 | 25.86 ± 6.49/23.43 ± 5.27 | ELISA | ||
Tam et al. 2016 [19] | China | 12.91 ± 0.63/12.96 ± 0.45 | 17.59 ± 2.10/18.35 ± 2.23 | 148/116 | 8.1 ± 7.48/10.47 ± 8.34 | 26.46 ± 6.66/23.98 ± 6.95 | 0.28/0.39 | ELISA | |
Wang et al. 2016 [17] | China | 12.81 ± 1.82/13.67 ± 1.67 | 17.66 ± 1.15/19.66 ± 0.91 | 31/15 | 7.62 ± 2.80/8.89 ± 4.15 | ELISA | |||
Yu et al. 2018 [20] | China | 12.43 ± 1.90/12.80 ± 1.22 | 17.83 ± 1.18/17.55 ± 1.35 | 105/40 | 6.55 ± 2.88/8.01 ± 3.12 | 6550 ± 2460/4460 ± 2020 | ELISA | ||
Gauzy et al. 2015 [22] | France | 14.3 ± 1.4/13.9 ± 1.6 | 19.1 ± 2.6/18.5 ± 2.5 | 49/15 | 261.9 ± 120.3/146.1 ± 59.2 | Radioimmunoassay | |||
Xiao et al. 2020 [21] | China | 14.52 ± 2.24/14.23 ± 2.04 | 17.76 ± 2.60/20.87 ± 4.54 | 83/44 | 27.33 ± 6.57/15.81 ± 3.82 | ELISA |