Weeks | Experimental group | Control group | P value | ||||
---|---|---|---|---|---|---|---|
MMP-13 (%) | IL-1β (ng/ml) | IL-17 (ng/ml) | MMP-13 (%) | IL-1β (ng/ml) | IL-17 (ng/ml) | ||
2 | 1.56 ± 0.21 | 17.54 ± 4.60 | 20.31 ± 8.45 | 1.28 ± 0.17 | 1.52 ± 1.60 | 1.31 ± 0.55 | < 0.05* |
4 | 12.24 ± 0.13 | 21.44 ± 6.70 | 24.41 ± 7.35 | 1.47 ± 0.21 | 1.54 ± 1.70 | 1.33 ± 0.45 | < 0.05* |
8 | 10.53 ± 0.25 | 25.53 ± 6.30 | 38.31 ± 6.53 | 1.17 ± 0.16 | 1.53 ± 1.50 | 1.32 ± 0.55 | < 0.05* |