Fig. 2
From: The protective effects of grape seed oil on induced osteoarthritis of the knee in male rat models
Pathological findings in rat models of OA; data are presented as mean ± standard deviation. Groups are named as C1, receiving no treatment; C2, receiving 300 mg/day of Piascledine per os (PO) for 10 weeks; C3, 1 mg sodium hyaluronate intra-articularly in days 1, 7, 14; C4, 1 mg methyl-prednisolone acetate intra-articularly in days 1, 7, 14; E1, avocado and grape seed oil combination (2:1, 300 mg/day) PO daily; E2, 500 mg/day of grape seed oil PO daily; E3, 200 mg/day grape seed oil intra-articularly in days 1, 7, 14. *P < 0.05 E1 and E3 versus other treatment groups. †P < 0.05 E1 or E3 versus other groups treated via the same route (PO or intra-articular). **P < 0.05 treatment group versus non-treated group (C1)