Table 2 Detail treatment protocols of PRP and HA injections
From: Platelet-rich plasma versus hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis
Author | PRP | HA | |||||
|---|---|---|---|---|---|---|---|
Injection dose (ml) | Times | Intervals | Type | Injection dose (ml) | Times | Intervals | |
Ahmad 2018 [22] | 4 | 3 | 2 Weeks | LRP | 20 mg/2 ml high | 3 | 2 Weeks |
Buendia-Lopez 2018 [23] | 5 | NS | NS | LPP | 60 mg/2 ml high | NS | NS |
Cerza 2012 [24] | 5.5 | 4 | Weekly | LPP | 20 mg/2 ml high | 4 | Weekly |
Cole 2017 [20] | 4 | 3 | Weekly | LPP | 16 mg/2 ml high (6 MDa) | 3 | Weekly |
Di Martino 2019 [25] | 5 | 3 | Weekly | LRP | 30 mg/2 ml high (> 1500 kDa) | 3 | Weekly |
Duymus 2017 [26] | 5 | 2 | Monthly | LRP | 40 mg/2 ml high (1600 kDa) | 1 | Monthly |
Filardo 2015 [19] | 5 | 3 | Weekly | LRP | 30 mg/2 ml high (> 1500 kDa) | 3 | Weekly |
Gormeli 2017 [27] | 5 | 3 | Weekly | LRP | 30 mg/2 ml | 3 | Weekly |
Huang 2019 [28] | 2 | 3 | Weekly | LPP | 4 ml (500–730 kDa) | 3 | Weekly |
Li 2011 [29] | 3.5 | 3 | 3 Weeks | LRP | 2 ml | 3 | 3 Weeks |
Lin 2019 | 5 | 3 | Weekly | LPP | 20 mg/2 ml | 3 | Weekly |
Louis 2018 [30] | 3 | 1 | NS | LPP | 60 mg/3 ml | 1 | NS |
Montanez-Heredia 2016 [31] | NS | 3 | 2 Weeks | LPP | NS | 3 | 2 Weeks |
Paterson 2016 [32] | 3 | 3 | Weekly | LRP | 3 ml | 3 | Weekly |
Raeissadat 2015 [33] | 43,927 | 2 | Monthly | LRP | 20 mg/2 ml (500–730 kDa) | 3 | Weekly |
Sanchez 2012 [34] | 8 | 3 | Weekly | LPP | NS | 3 | Weekly |
Su 2018 [35] | 6 | 2 | 2 Weeks | LRP | 2 ml | 5 | Weekly |
Vaquerizo 2013 [36] | 8 | 3 | 2 Weeks | LPP | NS | 1 | NS |
Yu 2018 [37] | 2–14 | 4 | Weekly | LRP | 0.1–0.3 mg | 4 | Weekly |
Tavassoli 2019 [38] | 4–6 | 4 | 3 Weeks | LRP | 30 mg/2 ml (500–730 kDa) | 4 | Weekly |