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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Increasing the level of cytoskeletal protein Flightless I reduces adhesion formation in a murine digital flexor tendon model

Fig. 6

FliiTg/Tg mice have slower, more organised collagen deposition within the adhesion and significantly decreased adhesion score. (a-d) Representative images of tendon adhesions in WT (a-b) and FliiTg/Tg (c-d) mice at days 21 and 28 post-injury, stained with Masson’s trichrome. Dotted line represents adhesion area; t, tendon. Magnification × 20, scale bar = 200 μM. (e) Graph showing significantly decreased collagen deposition in the healing tendons of FliiTg/Tg mice compared with WT at day 21 and 28. (f) Graph showing decreased adhesion score indicative of collagen fibres appearing more similar to those of unwounded tendons. n = 6. Data represented as mean ± SEM. *p ≤ 0.05

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