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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Increasing the level of cytoskeletal protein Flightless I reduces adhesion formation in a murine digital flexor tendon model

Fig. 5

Adhesions in FliiTg/Tg mice have upregulated Flii levels. Representative images immunostained for Flii expression in WT (a-e) and FliiTg/Tg (f-j) mice from days 3, 7, 14, 21 and 28 post-injury. Flii expression is detected as red fluorescence and DAPI staining detected as blue fluorescence. t, tendon; d, dermis; dotted line, adhesion area. Magnification × 10. Scale bar = 200 μM and refers to all images. (k) Graphical representation of Flii expression in the tendon adhesions of WT and FliiTg/Tg mice at 7, 14, 21 and 28 days post 50% partial laceration injury. No adhesions were detected at day 3 post injury. n = 6. Data represented as mean ± SEM. *p ≤ 0.05

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