Fig. 3
FliiTg/Tg mice have slower skin re-epithelialisation and increased epidermal thickness. (a-d) Representative images of H&E stained digits, showing the area of skin injury carried out to allow access to the tendon in WT and FliiTg/Tg mice at days 3 and 7. Images illustrate the significantly delayed re-epithelialisation and increased epidermal thickness in FliiTg/Tg mice compared with WT mice. W, wound; D, dermis; E, epidermis. Arrows indicate edge of wound. Magnification × 10. Scale bar = 200 μM. n = 6. (e) Graph showing average wound gape at day 3 in WT and FliiTg/Tg mice. (f) Graph showing average epidermal thickness of WT and FliiTg/Tg mice at days 3 and 7. n = 6, mean ± SEM. *p ≤ 0.05, **p ≤ 0.01