Fig. 4
From: Lupeol inhibits osteosarcoma progression by up-regulation of HMGA2 via regulating miR-212-3p
Identification of HMGA2 targeting miR-212-3p. a The binding sites between miR-212-3p in HMGA2 were predicted by starBase v2.0. b, c The relative luciferase activity of MNNG/HOS and MG-63 cells co-transfected with the miR-212-3p and pMIR-REPOR-SNHG1-WTor pMIR-REPOR-SNHG1-mut was measured. d, f The mRNA and protein expression levels of miR-145-5p on MNNG/HOS and MG-63 cells transfected with miR-NC andmiR-212-3p overexpression vector. e, g The mRNA and protein expression of HMGA2 was evaluated after transfection the miR-145-5p inhibitor into MNNG/HOS and MG-63 cells. *P < 0.05, n = 3