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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Lupeol inhibits osteosarcoma progression by up-regulation of HMGA2 via regulating miR-212-3p

Fig. 2

Lupeol, as well as overexpression of miR-212-3p, inhibited cell proliferation and invasion promoted apoptosis in osteosarcoma cells. a The miR-212-3p expression in MNNG/HOS and MG-63 cells was tested by qRT-PCR. b, c MTT assay was used to detect cell viability of MNNG/HOS and MG-63 cells with overexpression of miR-212-3p at the indicated time points. d, e Flow cytometry was used to detect apoptosis of MNNG/HOS and MG-63 cells after transfection for 24 h. f Transwell invasion assay was performed to determine the numbers of invaded cells. *P < 0.05, n = 3

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