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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: LncRNA SNHG10 increases the methylation of miR-218 gene to promote glucose uptake and cell proliferation in osteosarcoma

Fig. 3

High glucose inducible SNHG10 and miR-218 regulated glucose uptake in OS cells. U2OS and MG-63 cells were treated with medium contaning 10, 20, 30, 40, and 50 mM D-glucose for 48 h, followed by the measurement of the expression levels of SNHG10 (a) and miR-218 (b) through RT-qPCR. To explore the role of SNHG10 and miR-218 in regulating glucose uptake in OS cells, U2OS and MG-63 cells were transfected with SNHG10 expression vector (c) or miR-218 mimic (d), followed by glucose uptake. Three biological replicates were included in each experiment and mean ± SD values were presented and compared. *p < 0.05

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