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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: LncRNA SNHG10 increases the methylation of miR-218 gene to promote glucose uptake and cell proliferation in osteosarcoma

Fig. 2

Overexpression of SNHG10 downregulated miR-218 through methylation. Overexpression of SNHG10 and miR-218 in U2OS and MG-63 cells were confirmed by RT-qPCR (a). The effects of overexpression of SNHG10 on miR-218 (b), and the effects of overexpression of miR-218 on SNHG10 (c) were also analyzed by RT-qPCR. MSP was performed to analyze the role of SNHG10 in regulating the methylation of miR-218 (d). Three biological replicates were included in each experiment and mean ± SD values were presented and compared. M, methylation; U, unmethylation; *p < 0.05

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