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Table 1 Clinical characteristics of patients with postmenopausal osteoporosis and glucocorticoid-induced osteoporosis

From: Evaluation of risk factors of vertebral fracture in Japanese female patients with glucocorticoid-induced osteoporosis

 

Postmenopausal osteoporosis (n = 72)

Glucocorticoid-induced osteoporosis (n = 225)

p value

Premenopausal (%)

 

144 (64)

 

Postmenopausal (%)

72 (100)

81 (36)

 

Age (years)

76.4 (8.16)

49.7 (15.6)

< 0.0001***

Height (cm)

148.4 (8.42)

156.5 (7.07)

< 0.0001***

Bodyweight (kg)

48.2 (8.4)

53.3 (11.1)

0.013*

Body mass index

21.9 (3.45)

21.8 (4.08)

0.71

Bone mineral density (g/cm2)

   

 Lumbar spine

0.775 (0.118)

0.884 (0.13)

< 0.0001***

 Femoral neck

0.541 (0.12)

0.654 (0.118)

< 0.0001***

 Total hip

0.639 (0.114)

0.753 (0.125)

< 0.0001***

 Vertebral fracture (%)

30 (41.7)

62 (27.6)

 

Medical conditions necessitating glucocorticoid therapy

   

 Rheumatoid arthritis (%)

 

57 (25.3)

 

 Systemic lupus erythematosus (%)

 

148 (65.8)

 

 Others (%)

 

20 (8.9)

 

Disease duration (years)

 

15.9 (10.5)

 

Disease duration subtracted from age (years)

 

33.7 (14.8)

 

Glucocorticoid treatment duration (years)

 

14.4 (10.1)

 

Daily prednisone-equivalent dose (mg)

 

8.1 (3.42)

 

Cumulative prednisone-equivalent dose (g)

 

402.9 (387.6)

 

Treatment for osteoporosis

   

 Bisphosphonate (%)

61 (84.7)

172 (76.4)

 

 Denosumab (%)

11 (15.3)

53 (22.6)

 
  1. Results are expressed as the mean and standard deviation
  2. *p < 0.05
  3. ***p < 0.001 by Mann–Whitney U test