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Table 5 Univariate and multivariate analysis of overall survival rates based on primary site and disease stage

From: Influence of marital status on overall survival in adult patients with chordoma: a SEER-based study

Characteristic

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Primary site

Bones of skull and face and associated joints

 

< 0.001

 

0.017

 Married

Reference

 

Reference

 

 Divorced/separated

2.01 (1.14–3.56)

0.016

2.31 (1.26–4.22)

0.007

 Widowed

4.33 (2.35–8.00)

< 0.001

2.34 (1.18–4.65)

0.015

 Single

0.74 (0.45–1.21)

0.233

1.15 (0.67–1.95)

0.618

Vertebral column

 

< 0.001

 

0.011

 Married

Reference

 

Reference

 

 Divorced/separated

0.81 (0.44–1.51)

0.514

0.94 (0.48–1.86)

0.863

 Widowed

3.33 (2.11–5.26)

< 0.001

2.43 (1.44–4.12)

0.001

 Single

0.66 (0.39–1.10)

0.111

0.82 (0.48–1.43)

0.488

Pelvic bone, sacrum, coccyx, and associated joints

 

0.064

 

0.277

 Married

Reference

 

Reference

 

 Divorced/separated

1.26 (0.72–2.19)

0.423

1.24 (0.69–2.25)

0.477

 Widowed

1.74 (1.12–2.71)

0.014

0.96 (0.57–1.60)

0.867

Single

1.36 (0.90–2.05)

0.140

1.54 (0.99–2.38)

0.056

Disease stage

Localized

 

< 0.001

 

0.483

 Married

Reference

 

Reference

 

 Divorced/separated

1.15 (0.62–2.17)

0.655

1.17 (0.60–2.29)

0.650

 Widowed

3.54 (2.16–5.80)

< 0.001

1.54 (0.89–2.67)

0.126

 Single

0.79 (0.48–1.29)

0.340

1.20 (0.70–2.06)

0.519

Regional

 

< 0.001

 

0.055

 Married

Reference

 

Reference

 

 Divorced/separated

1.22 (0.77–1.93)

0.401

1.31 (0.81–2.11)

0.266

 Widowed

2.80 (1.82–4.32)

< 0.001

1.95 (1.23–3.10)

0.005

 Single

0.69 (0.45–1.04)

0.073

1.09 (0.71–1.67)

0.702

Distant

 

< 0.001

 

0.159

 Married

Reference

 

Reference

 

 Divorced/separated

6.83 (2.25–20.73)

0.001

4.43 (1.19–16.53)

0.027

 Widowed

2.78 (1.14–6.80)

0.025

3.14 (0.71–13.99)

0.133

 Single

1.31 (0.69–2.48)

0.405

1.33 (0.58–3.04)

0.497