Fig. 4

Result of the histological scoring. For the bone cross-sectional area, there is no significant difference (a). Also, for bone maturity, no significant difference can be observed between the groups (b). The osteogenic cellular activity is significantly higher in all granulate-treated defects compared to the empty defect and the control group (c). *p ≤ 0.05; **p ≤ 0.01; n.s., not significant