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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy

Fig. 5

Suppression of autophagy weakened the inhibitory effect of BNIP3 on the inflammation injury and apoptosis of chondrocytes. a The levels of IL-1β, IL-6, and TNF-α in the supernatant of chondrocytes were determined with ELISA assays after the inhibition of autophagy. b, c The apoptosis rates of chondrocytes were detected with the flow cytometry after the suppression of autophagy. d Apoptosis-related proteins in chondrocytes was detected with the western blotting after the inhibition of autophagy. *p < 0.05, **p < 0.01, ***p < 0.001

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