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Table 1 The characteristics of included studies

From: Outcomes of platelet-rich plasma for plantar fasciopathy: a best-evidence synthesis

Study(Year)

Sex,na,(M/F)b

Age,Mean(SD)

Groups,n

Treatment Schedules

Assessment Methods

Follow-up, Month

PRP

CS/PL

PRP

CS/PL

Omar AS (2012) [32]

30(0/30)

PRP:42.5(17.5)

CS:44.5(15.5)

15

15

1 dose of P-PRP was injected

1 dose of CS injected

VAS; FHSQ

1

Lee TG (2007) [33]

64/(4/57)

PRP:48.3(10.5)

CS:49.2(11.1)

30

31

1 dose(1.5 ml) of autologous blood mixed with 1 ml of Lignocaine HCL 2% was injected

a combination of 20 mg (0.5 ml of a 40 mg/ml solution) of Triamcinolone Acetonide with 2 ml of Lignocaine HCL 1% was used

VAS; TT

1;3;6

Aksahin E (2012) [34]

60(25/35)

PRP:46.36(8.49)

CS:45.47(9.36)

30

30

1 dose(3mL) P-PRP was injected after 2 mL of 2% prilocaine injection

1 does of 2 mL of 40 mg Methylprednisolone with 2 mL of 2% prilocaine was injected

VAS; MRMS

6

Carlos AO (2017) [35]

32(6/24)

PRP:44.8(0)

CS:44.8(0)

15

15

1 dose of P-PRP(3 mL) activated with 0.45 mL of 10% calcium gluconate was injected

1 dose (8 mg) of dexamethasone plus 2 mL of lidocaine was injected

VAS; FADI; AOFAS

1;2;3;4

Tiwari M (2013) [36]

60(3/57)

NC

30

30

1 dose(5ml) of P-PRP was injected

1 dose of CS was injected

VAS

1;3;6

Monto RR (2014) [13]

40(17/23)

PRP:59(0)

CS:51(0)

20

20

a single ultra-sound guided injection of autologous P-PRP was injected

a single ultrasound guided injection of 40 mg DepoMedrol cortisone

AOFAS

3;6;12;24

Jain K (2015) [37]

46(6/40)

PRP:55.6(0)

CS:55.6(0)

23

23

1 dose(2.5ml) of P-PRP was injected

1 dose of Triamcinolone (Kenalog) 40 mg and Levobupivacaine hydrochloride (Chirocaine) injection

VAS; AOFAS; MRMS

3;6;12

Say F (2014) [38]

50(11/39)

PRP:47(0)

CS:48.6(0)

25

25

1 dose(2.5ml) of P-PRP was injected

1 dose of a mixture of 40 mg/1 ml of methylprednisolone and 1 ml of prilocaine was injected

VAS; AOFAS

6

Sherpy NA (2016) [39]

50(13/37)

PRP:37.48(8.75)

CS:38.52(6.2)

25

25

1 dose(3ml) of P-PRP was injected

1 dose of triamcinolone acetonide (2ml ,40 mg/ml) was injected

VAS; FHSQ

1.5;3

Vahdatpour B (2016) [40]

32(9/23)

PRP:45.44(7.74)

CS:47.12(10.70)

16

16

1 dose(3ml) of P-PRP was injected

1 dose of Methylprednisolone( 1 ml) plus lidocaine( 1 ml) was injected

VAS; MRMS

1;3;6

Jain SK (2018) [41]

80(46/34)

PRP:37.7(10.3)

CS:38.9(9.5)

40

40

1 dose(3ml) of P-PRP was injected

1 dose of methyl prednisolone (2m,40 mg) with 2% lidocaine hydrochloride(2 mL) was injected

VAS; MRMS; AAOS; FAI; AOFAS

1;3;6

Sarah JL (2019) [42]

28(9/19)

PRP:47.9(10.702)

Placebo:52.1(10.277)

14

14

1 dose(3ml) of P-PRP was injected

1 dose of saline injected

VAS

6

Mahindra P (2016) [43]

75(31/44)

PRP:30.72(7.42)

CS:33.92(8.61)

Pl:35.48(9.54)

25

25

1 dose(3ml) of P-PRP was injected

CS:1 dose of CS injected

PL:1 dose of saline injected

VAS; AOFAS

3

  1. NC Not clear, M Male, F Female, PL Placebo VAS visual analog scale, FHSQ foot health status questionnaire, TT tenderness threshold, MRMS ModiWed Roles and Maudsley score, FADI Foot Ankle Disability Index, AOFAS American Orthopaedic Foot and Ankle Society, FAI Foot and Ankle Outcome Instrument, AAOS merican Academy of Orthopedic Surgeons