Table 1 MSIS criteria for diagnosis of PJI (modified by ICM in 2018) [7]
From: D-dimer in the diagnosis of periprosthetic joint infection: a systematic review and meta-analysis
Major criteria | 1. Two positive periprosthetic cultures with phenotypically identical organisms | |||
2. A sinus tract communicating with the joint | ||||
Minor criteria | 3. Preoperative diagnosis | Score | Decision | |
Serum | 1).CRP (> 1 mg/dL) OR D-dimer (> 850 ng/mL) | 2 | ≥ 6: Infected 2–5: Possibly infected 0–1: Not infected | |
2). ESR (> 30 mm/h) | 1 | |||
Synovial | 1). Synovial WBC count (> 3000 cells/uL) or LE + | 3 | ||
2). Alpha-defensin (signal-to cut-off ratio > 1) | 3 | |||
3). Synovial PMN (%) (> 80%) | 2 | |||
4). Synovial CRP (> 6.9 mg/L) | 1 | |||
4. Intraoperative diagnosis. | Score | ≥ 6: Infected 4–5: Inconclusive ≤ 3: Not infected | ||
1). Preoperative score | – | |||
2). Histology | 3 | |||
3). Purulence | 3 | |||
4). Single culture | 2 | |||