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Table 1 Basic characteristics of included studies

From: The utility of 18F-FDG PET and PET/CT in the diagnosis and staging of chondrosarcoma: a meta-analysis

AuthorYearCountryDesignNumber of subjectsNo. of patients with chondrosarcomaGender (M/F)Age (mean, years)Type of cartilaginous bone neoplasmsInclusion intervalImagingCutoff value of SUVmaxInjected doseReference test
Annovazzi et al. [14]2019ItalyR956040/5553 ± 15Enchondroma and chondrosarcoma2011-2017PET and PET/CT2.65 MBq/kgPost-surgical histology diagnosis, clinical and radiologic follow-up
Purandare et al. [15]2019IndiaR6640NRNRChondrosarcoma, enchondroma, and osteochondroma2008.1-2018.6PET/CT3.15 MBq/kgPost-surgical or a bioptic-histological diagnosis, clinical and radiologic follow-up
Vadi, et al [16]2018IndiaR31NR20/2142.19 (17-69)Chondrosarcoma2010.1-2016.12PET/CTNR300-370 MBqPooled information from histological results and clinical or imaging follow-up
Jesus-Garcia et al. [12]2016BrazilP361912/2444 (21-68)Enchondroma and chondrosarcoma2009.10-2015.5PET/CT2.23.7 MBq/kgPost-surgical histological diagnosis, clinical and radiologic follow-up
Costelloe et al. [20]2013USAR185NRNREnchondroma and chondrosarcoma2007.1.1-2010.10.1PET/CTNR370 MBq or 555-740 MBqPooled information from histological results and clinical or imaging follow-up
Purandare et al. [21]2009IndiaR1247/529.9 ± 11.6 (15-50)Osseocartilaginous tumor, chondrosarcoma2005-2007PET/CT1.3/3.3370 MBqPooled information from histological results and clinical or imaging follow-up
Shin et al. [22]2008South KoreaR126NRNRChondroblastoma, chondroma, enchondroma, and chondrosarcoma2004.5-2007.6PET/CT3.88.14 MBq/kgPooled information from histological results and clinical or imaging follow-up
Strobel et al. [23]2008SwitzerlandP73NRNRChondrosarcoma, osteochondroma, chondroblastoma, and enchondromaNRPET2.5350-400 MBqPooled information from histological results and clinical or imaging follow-up
Feldman et al. [24]2005USAR29189/2053 ± 17.58 (11-85)Enchondroma, osteochondroma, and chondrosarcoma2000-2003PET25.18 MBq/kgPooled information from histological results and clinical or imaging follow-up
Brenner et al. [25]2004USAR313117/1450.4 ± 14.3 (23-85)Chondrosarcoma1995.5-2002.5PETNR370 MBqPost-surgical histology diagnosis
Lee et al. [26]2004USAR271318/9NREnchondroma, osteochondroma, and chondrosarcoma1999-2002PETNR5.18 MBq/kgHistopathologic examination
Aoki et al. [27]1999JapanP1154/744.3 ± 21.0 (12-78)Enchondroma, osteochondroma, and chondrosarcoma1997.8-1998.12PET1.35 MBq/kgHistopathologic examination
  1. P prospective; R retrospective; NR not reported; PET positron emission tomography; CT computed tomography