|
Characteristics
|
Calcitonin (n = 66)
|
Celecoxib (n = 57)
|
P value
|
|---|
|
Pain VAS scores (0–10)
| | | |
|
Baseline
|
6.48 ± 1.08
|
6.52 ± 0.87
|
0.876
|
|
1 week
|
4.95 ± 1.28*
|
5.76 ± 0.89*
|
0.022
|
|
2 weeks
|
3.71 ± 0.96*
|
4.62 ± 0.92*
|
0.003
|
|
4 weeks
|
2.95 ± 0.80*
|
3.57 ± 0.87*
|
0.021
|
|
3 months
|
1.86 ± 0.65*
|
2.57 ± 0.81*
|
0.008
|
|
WOMAC scores
| | | |
|
Total scores (0–96)
| | | |
|
Baseline
|
54.09 ± 10.24
|
54.60 ± 10.88
|
0.878
|
|
1 week
|
41.00 ± 8.84*
|
49.89 ± 10.45
|
0.005
|
|
2 weeks
|
35.07 ± 7.43*
|
44.24 ± 10.10*
|
0.002
|
|
4 weeks
|
31.45 ± 6.67*
|
39.80 ± 8.63*
|
0.001
|
|
3 months
|
26.92 ± 6.81*
|
36.01 ± 7.93*
|
< 0.001
|
|
Pain scores (0–20)
| | | |
|
Baseline
|
12.08 ± 4.09
|
12.15 ± 2.62
|
0.943
|
|
1 week
|
8.89 ± 3.25*
|
10.87 ± 2.41
|
0.031
|
|
2 weeks
|
7.57 ± 2.53*
|
9.82 ± 2.06*
|
0.003
|
|
4 weeks
|
6.82 ± 2.19*
|
8.48 ± 1.80*
|
0.011
|
|
3 months
|
5.78 ± 1.55*
|
7.70 ± 1.63*
|
< 0.001
|
|
Stiffness scores (0–8)
| | | |
|
Baseline
|
4.95 ± 0.97
|
4.90 ± 0.70
|
0.857
|
|
1 week
|
4.10 ± 0.89*
|
4.62 ± 0.67
|
0.037
|
|
2 weeks
|
3.29 ± 0.90*
|
3.95 ± 0.86*
|
0.019
|
|
4 weeks
|
2.67 ± 0.86*
|
3.62 ± 0.67*
|
0.001
|
|
3 months
|
2.00 ± 0.84*
|
2.95 ± 0.92*
|
< 0.001
|
|
Physical function scores (0–68)
| | | |
|
Baseline
|
37.07 ± 9.54
|
37.54 ± 11.31
|
0.883
|
|
1 week
|
28.02 ± 8.11*
|
34.40 ± 11.00
|
0.039
|
|
2 weeks
|
24.21 ± 7.15*
|
30.48 ± 9.47*
|
0.020
|
|
4 weeks
|
21.96 ± 6.44*
|
27.70 ± 9.04*
|
0.023
|
|
3 months
|
19.14 ± 6.84*
|
25.35 ± 8.39*
|
0.012
|
- VAS visual analog scale, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index
- *P < 0.05 vs baseline
