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Table 2 Comparison of clinical outcomes between two groups

From: Clinical effect of intramuscular calcitonin compared with oral celecoxib in the treatment of knee bone marrow lesions: a retrospective study

Characteristics Calcitonin (n = 66) Celecoxib (n = 57) P value
Pain VAS scores (0–10)    
 Baseline 6.48 ± 1.08 6.52 ± 0.87 0.876
 1 week 4.95 ± 1.28* 5.76 ± 0.89* 0.022
 2 weeks 3.71 ± 0.96* 4.62 ± 0.92* 0.003
 4 weeks 2.95 ± 0.80* 3.57 ± 0.87* 0.021
 3 months 1.86 ± 0.65* 2.57 ± 0.81* 0.008
WOMAC scores    
Total scores (0–96)    
 Baseline 54.09 ± 10.24 54.60 ± 10.88 0.878
 1 week 41.00 ± 8.84* 49.89 ± 10.45 0.005
 2 weeks 35.07 ± 7.43* 44.24 ± 10.10* 0.002
 4 weeks 31.45 ± 6.67* 39.80 ± 8.63* 0.001
 3 months 26.92 ± 6.81* 36.01 ± 7.93* < 0.001
Pain scores (0–20)    
 Baseline 12.08 ± 4.09 12.15 ± 2.62 0.943
 1 week 8.89 ± 3.25* 10.87 ± 2.41 0.031
 2 weeks 7.57 ± 2.53* 9.82 ± 2.06* 0.003
 4 weeks 6.82 ± 2.19* 8.48 ± 1.80* 0.011
 3 months 5.78 ± 1.55* 7.70 ± 1.63* < 0.001
Stiffness scores (0–8)    
 Baseline 4.95 ± 0.97 4.90 ± 0.70 0.857
 1 week 4.10 ± 0.89* 4.62 ± 0.67 0.037
 2 weeks 3.29 ± 0.90* 3.95 ± 0.86* 0.019
 4 weeks 2.67 ± 0.86* 3.62 ± 0.67* 0.001
 3 months 2.00 ± 0.84* 2.95 ± 0.92* < 0.001
Physical function scores (0–68)    
 Baseline 37.07 ± 9.54 37.54 ± 11.31 0.883
 1 week 28.02 ± 8.11* 34.40 ± 11.00 0.039
 2 weeks 24.21 ± 7.15* 30.48 ± 9.47* 0.020
 4 weeks 21.96 ± 6.44* 27.70 ± 9.04* 0.023
 3 months 19.14 ± 6.84* 25.35 ± 8.39* 0.012
  1. VAS visual analog scale, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index
  2. *P < 0.05 vs baseline