Fig. 3
From: In vitro analysis of the effect of Flightless I on murine tenocyte cellular functions
Flii regulates tenocyte cellular migration. An in vitro scratch wound model was used to investigate the effect of differential Flii on tenocyte migration. a–c Representative images of scratch wounds in Flii+/−, WT, and FliiTg/Tg tenocytes at 24 h post-wounding. d–f Representative images of scratch wounds in Flii+/−, WT, and FliiTg/Tg fibroblasts at 24 h post-wounding. Magnification × 4. Scale bar = 300 μM. g Graph showing scratch closure in tenocytes expressed as percentage of original wound size. FliiTg/Tg tenocytes show significantly improved wound closure. h Graph showing scratch closure in fibroblasts expressed as percentage of original wound size. Flii+/− fibroblasts show significantly improved wound closure. *p ≤ 0.05 between Flii+/− and FliiTg/Tg. ^p ≤ 0.05 between Flii+/− and WT. +p ≤ 0.05 between FliiTg/Tg and WT. Data represented as mean ± SEM. n = 6