Skip to main content
Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: URG4 mediates cell proliferation and cell cycle in osteosarcoma via GSK3β/β-catenin/cyclin D1 signaling pathway

Fig. 2

URG4 affects vitro migration, invasion, colony formation, and vivo tumorigenesis. a HOS and MG63 cells stably transfected with siURG4 or siCtrl, and migration ability was evaluated by wound-healing assay. b Transwell assay was performed to analyze invasive ability. c Colony-forming abilities were researched by plate clones assay. d Images, volume, and weight of transplanted tumors in nude mice 31 days after subcutaneous inoculation with osteosarcoma cells stably expressing siURG4-1 or si-NC. URG4: upregulated gene 4; K: blank group; NC: negative control. *p < 0.05, **p < 0.01 vs the NC

Back to article page

Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X