From: PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway
Clinicopathological features | Number of cases (n) | PENK expression | P | |
---|---|---|---|---|
High (n) | Low (n) | |||
Age | ||||
< 25 years | 28 | 16 | 12 | 0.573 |
≥ 25 years | 12 | 8 | 4 | |
Gender | ||||
Male | 25 | 18 | 7 | 0.722 |
Female | 15 | 10 | 5 | |
Tumor size | ||||
> 8 cm | 22 | 10 | 12 | 0.949 |
≤ 8 cm | 18 | 8 | 10 | |
Anatomic location | ||||
Tibia/femur | 30 | 20 | 10 | 0.702 |
Elsewhere | 10 | 6 | 4 | |
Serum level of lactate dehydrogenase | ||||
Elevated | 25 | 15 | 10 | 0.191 |
Normal | 15 | 12 | 3 | |
Serum level of alkaline phosphatase | ||||
Elevated | 31 | 16 | 15 | 0.162 |
Normal | 9 | 7 | 2 | |
Clinical stage | ||||
IIA | 32 | 25 | 7 | 0.004 |
IIB/III | 8 | 2 | 6 | |
Pathology | ||||
Osteoblastic | 15 | 8 | 7 | 0.966 |
Chondroblastic | 10 | 5 | 5 | |
Fibroblastic | 10 | 6 | 4 | |
Telangiectatic | 5 | 3 | 2 | |
Metastasis | ||||
Absent | 30 | 15 | 15 | 0.583 |
Present | 10 | 6 | 4 |