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Table 1 Correlation of PENK expression with clinicopathological features of osteosarcoma

From: PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway

Clinicopathological features

Number of cases (n)

PENK expression

P

High (n)

Low (n)

Age

    

  < 25 years

28

16

12

0.573

  ≥ 25 years

12

8

4

Gender

    

  Male

25

18

7

0.722

  Female

15

10

5

Tumor size

    

  > 8 cm

22

10

12

0.949

  ≤ 8 cm

18

8

10

Anatomic location

    

  Tibia/femur

30

20

10

0.702

  Elsewhere

10

6

4

Serum level of lactate dehydrogenase

    

  Elevated

25

15

10

0.191

  Normal

15

12

3

Serum level of alkaline phosphatase

    

  Elevated

31

16

15

0.162

  Normal

9

7

2

Clinical stage

    

  IIA

32

25

7

0.004

  IIB/III

8

2

6

Pathology

    

  Osteoblastic

15

8

7

0.966

  Chondroblastic

10

5

5

  Fibroblastic

10

6

4

  Telangiectatic

5

3

2

Metastasis

    

  Absent

30

15

15

0.583

  Present

10

6

4