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Table 1 General characteristic of the included studies

From: Intrathecal versus local infiltration analgesia for pain control in total joint arthroplasty

AuthorCountryASACases (n, LIA/ITM)Mean age (years, LIA/ITM)Female patients (%, LIA/ITM)AnesthesiaDrug dose of LIADrug dose of ITMSurgeryFollow-upStudy
Andersen et al. [15]DenmarkI–III19/2169/6752/50SA300 mg ropivacaine + 0.5 mg epinephrine60 mg lidocaineTKA72 hRCT
Andersen et al. [16]DenmarkI–III37/3861/6138.9/42.4SA200 mg ropivacaine + 0.5 mg epinephrine60 mg lidocaineTHA14 daysRCT
Binici et al. [17]TurkeyII–III15/1569.4/70.241.2/40SA240 mg bupivacaine240 mg bupivacaineTKA48 hRCT
Essving et al. [18]SwedenI–III25/2571/7038.9/38.5SA300 mg ropivacaine + 0.1 mg epinephrine0.1 mg morphineTKA72 hRCT
Kuchalik et al. [19]SwedenI–III40/4066/6745.4/52.4SA300 mg ropivacaine + 0.1 mg epinephrine0.1 mg morphineTHANSRCT
Rikalainen-Salmi et al. [20]FinlandI–III30/3065/66NSSA120 mg bupivacaine0.1 mg morphineTHA72 hRCT
Spreng et al. [21]NorwayI–III33/3365.8/67.249.7/48.4SA142.5 ropivacaineFentanyl nsTKANSRCT
Tammachote et al. [22]ThailandNS28/2969/7051.2/53.6SA100 mg bupivacaine60 mg bupivacaine + 15 mg epinephrineTKA7 daysRCT
Tsukada et al. [23]JapanNS61/50NSNSSA200 mg ropivacaine + 0.3 mg epinephrine8 mg morphineTKANSRCT
Tsukada et al. [24]JapanNS33/37NSNSSA200 mg ropivacaine + 0.3 mg epinephrine200 mg ropivacaine + 8 mg morphineTKANSRCT
McCarthy et al. [13]IrelandI–III22/2166/64.319/43SALevobupivacaine 0.5% 2 mg kg 1 body weight and adrenaline 0.5 mg diluted to a total volume of 100 ml with 0.9% saline300 μg morphineTKA48 hRCT
  1. SA spinal anesthesia, TKA total knee arthroplasty, THA total hip arthroplasty, RCT randomized controlled trials, NS not stated