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Table 1 Baseline demographics and clinicopathological characteristics of all patients (metastatic and non-metastatic groups)

From: Risk factors for metastasis and poor prognosis of Ewing sarcoma: a population based study

CharacteristicAll patients(N = 1160, 100%)
Number (%)
Non-metastatic(N = 844, 72.8%)
Number (%)
Metastatic(N = 316, 27.2%)
Number (%)
p value
Age (years)   0.011*
 ≤ 10242 (20.9%)197 (23.3%)45 (14.2%) 
 11–20571 (49.2%)402 (47.6%)169 (53.5%) 
 21–30206 (17.8%)142 (16.8%)64 (20.3%) 
 31-49101 (8.7%)76 (9.0%)25 (7.9%) 
 ≥ 5040 (3.4%)27 (3.2%)13 (4.1%) 
Gender   0.926
 Male733 (63.2%)534 (63.3%)199 (63.0%) 
 Female427 (36.8%)310 (36.7%)117 (37.0%) 
Race   0.749
 White1041 (89.7%)759 (89.9%)282 (89.2%) 
 Black30 (2.6%)20 (2.4%)10 (3.2%) 
 Other*89 (7.7%)65 (7.7%)24 (7.6%) 
Primary site   < 0.001***
 Limb519 (44.7%)405 (48.0%)114 (36.1%) 
 Cranial66 (5.7%)60 (7.1%)6 (1.9%) 
 Spine88 (7.6%)71 (8.4%)17 (5.4%) 
 Thoracic173 (14.9%)129 (15.3%)44 (13.9%) 
 Pelvic314 (27.1%)179 (21.2%)135 (42.7%) 
Tumor size (cm)   < 0.001***
 < 5221 (19.1%)185 (21.9%)36 (11.4%) 
 5–8371 (32.0%)283 (33.5%)88 (27.8%) 
 > 8568 (49.0%)376 (44.5%)192 (60.8%) 
Tumor extent   -
 Localized311 (26.8%)311 (36.8%)0 (0.0%) 
 Regional533 (45.9%)533 (63.2%)0 (0.0%) 
 Metastatic316 (27.2%)0 (0.0%)316 (100.0%) 
Cancer-directed surgery   < 0.001***
 No390 (33.6%)213 (25.2%)177 (54.0%) 
 Yes770 (66.4%)631 (74.8%)139 (44.0%) 
Radiation   < 0.001***
 No584 (50.3%)468 (55.5%)116 (36.7%) 
 Yes576 (49.7%)376 (44.5%)200 (63.3%) 
Chemotherapy   0.49
 No40 (3.4%)31 (3.7%)9 (2.8%) 
 Yes1120 (96.6%)813 (96.3%)307 (97.2%) 
  1. p value < 0.05*, < 0.001***
  2. *Including Native American/Alaska Native, Asian/Pacific Islander