Vertebral intraosseous plasma rich in growth factor (PRGF-Endoret) infiltrations as a novel strategy for the treatment of degenerative lesions of endplate in lumbar pathology: description of technique and case presentation

Table 1 A pre- and post-treatment magnetic resonance imaging analyses performed at the L3/L4 disc space and corresponding vertebral level

Spine L3–L4 level	MRI pre-PRGF	MRI post-PRGF
Protrusion diameter (PD)	mm	mm
Cranio-caudal (CC)	8.2	7.3
Antero-posterior (AP)	2.8	2.8
Discal degeneration degree	Grade	Grade
Pfirrmann classification	V	V
Endplate degeneration degree	Grade	Grade
Modic changes	1	1
Total endplate score (TEPS)	5	5
Schmörl’s node diameter (SND)
L3-lower SND	mm	mm
Cranio-caudal (CC)	2.6	1.5
Latero-lateral (LL)	3.0	Unmeasurable
Antero-posterior (AP)	7.6	3.0
L4-upper SND	mm	mm
Cranio-caudal (CC)	5.9	4.5
Latero-lateral (LL)	13.5	11.5
Antero-posterior (AP)	17.5	17.0

According to axial and sagittal T2-weighted images (T2WI) of the lumbar spine, the networked medical imaging remote Workstation AW 4.3 (GE Healthcare International) was used to import, interpret, and process DICOM images from MRI scans to categorize and obtain measurements of the following MRI parameters: protrusion diameter (PD), disc degeneration degree (Pfirrmann classification), endplate degeneration degree (Modic changes and total endplate score), and Schmörl’s node diameter (SND)

ISSN: 1749-799X