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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Exosomes derived from platelet-rich plasma present a novel potential in alleviating knee osteoarthritis by promoting proliferation and inhibiting apoptosis of chondrocyte via Wnt/β-catenin signaling pathway

Fig. 3

Cytokine release (TNF-α) of chondrocytes: In vitro, the chondrocytes were co-culture with PBS, IL-1β (10 ng/mL), IL-1β (10 ng/mL) added different concentration of PRP-Exos and PRP-As for 24 h. Osteoarthritis chondrocytes were established with TNF-α release increasing significantly(&<0.05). Both PRP-Exos and PRP-As with different concentration could inhibit TNF-α release significantly (*P < 0.05). Results were detected by ELISA with presenting as mean ± SEM from three independent experiments

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X