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Table 9 Univariate analysis of postoperative bone cement leakage (n, %)

From: Therapeutic effect of percutaneous kyphoplasty combined with anti-osteoporosis drug on postmenopausal women with osteoporotic vertebral compression fracture and analysis of postoperative bone cement leakage risk factors: a retrospective cohort study

Factor

Leakage group (n = 25)

No leakage group (n = 87)

t2/Z

P

Age (years)

51.4 ± 3.4

51.0 ± 3.2

0.591

0.556

BMI (kg/m2)

23.40 ± 1.80

23.29 ± 1.87

0.316

0.753

Marital status

  

0.460

0.795

 Married

20 (80.00)

73 (83.91)

  

 Unmarried

2 (8.00)

4 (4.60)

  

 Divorced

3 (12.00)

10 (11.49)

  

Past medical history

    

 Hypertension

7 (28.00)

29 (33.33)

0.253

0.615

 Diabetes

6 (24.00)

26 (29.89)

0.330

0.566

 Hyperlipidemia

4 (16.00)

26 (29.89)

1.909

0.167

 Coronary heart disease

3 (12.00)

10 (11.49)

0.005

0.945

Place of residence

  

3.395

0.065

 City

18 (72.00)

76 (87.36)

  

 Rural area

7 (28.00)

11 (12.64)

  

Degree of education

  

0.485

0.486

 ≥ Senior high school

16 (64.00)

62 (71.26)

  

 < Senior high school

9 (36.00)

25 (28.74)

  

Causes

  

0.270

0.874

 Falling down

15 (6.00)

51 (58.62)

  

 Sprain

7 (28.00)

28 (32.18)

  

 Other

3 (12.00)

8 (9.20)

  

Site of injured vertebrae

  

−0.065

0.948

 T7

2 (7.41)

8 (6.84)

  

 T8

0 (0.00)

2 (1.71)

  

 T9

1 (3.70)

4 (3.42)

  

 T10

2 (7.41)

7 (5.89)

  

 T11

3 (11.11)

8 (6.84)

  

 T12

5 (18.52)

26 (22.22)

  

 L1

4 (14.81)

22 (18.80)

  

 L2

3 (11.11)

15 (12.82)

  

 L3

3 (11.11)

12 (10.26)

  

 L4

3 (11.11)

9 (7.69)

  

 L5

1 (3.70)

4 (3.42)

  

Use of zoledronic acid

  

0.535

0.465

 Used

10 (15.00)

42 (48.28)

  

 Unused

15 (85.00)

45 (51.72)

  

Fracture acuteness

  

0.015

0.902

 Acute

15 (60.00)

51 (58.62)

  

 Subacute

10 (40.00)

36 (41.38)

  

Peripheral vertebrae wall damage

  

11.092

0.001

 Damaged

12 (48.00)

14 (16.09)

  

 Undamaged

13 (52.00)

73 (83.91)

  

Bone cement dosage (mL)

5.58 ± 1.53

4.20 ± 0.91

5.889

< 0.001

TNF-α (pg/mL)

5.76 ± 1.91

6.12 ± 2.76

0.790

0.430

IL-6 (pg/mL)

10.73 ± 3.04

11.16 ± 3.52

0.686

0.494

BMD (g/cm2)

0.92 ± 0.17

0.91 ± 0.15

0.330

0.742

PINP (μg/L)

54.73 ± 6.32

54.43 ± 6.15

0.254

0.800

BGP (μg/L)

4.16 ± 0.73

4.13 ± 0.84

0.842

0.200

Vertebral height ratios of injured vertebrae (%)

74.61 ± 11.40

73.33 ± 8.90

0.666

0.507

Cobb angle (°)

16.98 ± 2.84

16.55 ± 3.04

0.443

0.770

VAS score

3.04 ± 1.65

2.60 ± 1.30

1.577

0.118

ODI score

29.48 ± 10.06

30.26 ± 9.50

0.422

0.674

  1. BMI body mass index, TNF-α tumor necrosis factor-α, IL-6 Interleukin-6, BMD bone mineral density, PINP procollagen type I N-terminal propeptide, BGP bone gla protein, VAS visual analogue scale/score, ODI Oswestry disability index